Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort

Sara Grioni; Claudia Agnoli; Sabina Sieri; Valeria Pala; Fulvio Ricceri; Giovanna Masala; Calogero Saieva; Salvatore Panico; Amalia Mattiello; Paolo Chiodini; Rosario Tumino; Graziella Frasca; Licia Iacoviello; Amalia de Curtis; Paolo Vineis; Vittorio Krogh

doi:10.1371/journal.pone.0126550

Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort

Sara Grioni, Claudia Agnoli, Sabina Sieri, Valeria Pala, Fulvio Ricceri, Giovanna Masala, Calogero Saieva, Salvatore Panico, Amalia Mattiello, Paolo Chiodini, Rosario Tumino, Graziella Frasca, Licia Iacoviello, Amalia de Curtis, Paolo Vineis, Vittorio Krogh

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The relationship between coffee consumption and coronary heart disease (CHD) has been investigated in several studies with discrepant results. We examined the association between Italian-style (espresso and mocha) coffee consumption and CHD risk. Methods: We investigated 12,800 men and 30,449 women without history of cardiovascular disease recruited to the EPICOR prospective cohort study. Coffee consumption was assessed at baseline. In a random sub-cohort of 1472 subjects, plasma triglycerides, and total, LDL and HDL cholesterol were determined to investigate the effect of coffee consumption on plasma lipids. Results: After a mean follow up of 10.9 years, 804 cases of CHD (500 acute events, 56 fatal events and 248 revascularizations, all first events) were identified. Multivariable adjusted hazard ratios for CHD were: 1.18 (95% CI 0.87-1.60) for drinking 1- 2 cups/day, 1.37 (95% CI 1.03-1.82) for >2-4 cups/day and 1.52 (95% CI 1.11-2.07) for over 4 cups/day (P trend >0.001) compared to reference (>1 cup/day). Plasma triglycerides, and total, LDL and HDL cholesterol did not vary significantly (ANOVA) with coffee consumption.

Original language	English
Article number	e0126550
Journal	PLoS One
Volume	10
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0126550
Publication status	Published - May 6 2015

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

Access to Document

10.1371/journal.pone.0126550

Fingerprint Dive into the research topics of 'Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort'. Together they form a unique fingerprint.

Cite this

Grioni, S., Agnoli, C., Sieri, S., Pala, V., Ricceri, F., Masala, G., Saieva, C., Panico, S., Mattiello, A., Chiodini, P., Tumino, R., Frasca, G., Iacoviello, L., de Curtis, A., Vineis, P., & Krogh, V. (2015). Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort. PLoS One, 10(5), [e0126550]. https://doi.org/10.1371/journal.pone.0126550

Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort. / Grioni, Sara; Agnoli, Claudia ; Sieri, Sabina ; Pala, Valeria; Ricceri, Fulvio; Masala, Giovanna; Saieva, Calogero; Panico, Salvatore; Mattiello, Amalia; Chiodini, Paolo; Tumino, Rosario; Frasca, Graziella; Iacoviello, Licia ; de Curtis, Amalia; Vineis, Paolo; Krogh, Vittorio.

In: PLoS One, Vol. 10, No. 5, e0126550, 06.05.2015.

Research output: Contribution to journal › Article › peer-review

Grioni, Sara ; Agnoli, Claudia ; Sieri, Sabina ; Pala, Valeria ; Ricceri, Fulvio ; Masala, Giovanna ; Saieva, Calogero ; Panico, Salvatore ; Mattiello, Amalia ; Chiodini, Paolo ; Tumino, Rosario ; Frasca, Graziella ; Iacoviello, Licia ; de Curtis, Amalia ; Vineis, Paolo ; Krogh, Vittorio. / Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort. In: PLoS One. 2015 ; Vol. 10, No. 5.

@article{fd5a1bcb6db349c0bd400136975cf522,

title = "Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort",

abstract = "Background: The relationship between coffee consumption and coronary heart disease (CHD) has been investigated in several studies with discrepant results. We examined the association between Italian-style (espresso and mocha) coffee consumption and CHD risk. Methods: We investigated 12,800 men and 30,449 women without history of cardiovascular disease recruited to the EPICOR prospective cohort study. Coffee consumption was assessed at baseline. In a random sub-cohort of 1472 subjects, plasma triglycerides, and total, LDL and HDL cholesterol were determined to investigate the effect of coffee consumption on plasma lipids. Results: After a mean follow up of 10.9 years, 804 cases of CHD (500 acute events, 56 fatal events and 248 revascularizations, all first events) were identified. Multivariable adjusted hazard ratios for CHD were: 1.18 (95% CI 0.87-1.60) for drinking 1- 2 cups/day, 1.37 (95% CI 1.03-1.82) for >2-4 cups/day and 1.52 (95% CI 1.11-2.07) for over 4 cups/day (P trend >0.001) compared to reference (>1 cup/day). Plasma triglycerides, and total, LDL and HDL cholesterol did not vary significantly (ANOVA) with coffee consumption.",

author = "Sara Grioni and Claudia Agnoli and Sabina Sieri and Valeria Pala and Fulvio Ricceri and Giovanna Masala and Calogero Saieva and Salvatore Panico and Amalia Mattiello and Paolo Chiodini and Rosario Tumino and Graziella Frasca and Licia Iacoviello and {de Curtis}, Amalia and Paolo Vineis and Vittorio Krogh",

year = "2015",

month = may,

day = "6",

doi = "10.1371/journal.pone.0126550",

language = "English",

volume = "10",

journal = "PLoS One",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "5",

}

TY - JOUR

T1 - Espresso coffee consumption and risk of coronary heart disease in a large Italian cohort

AU - Grioni, Sara

AU - Agnoli, Claudia

AU - Sieri, Sabina

AU - Pala, Valeria

AU - Ricceri, Fulvio

AU - Masala, Giovanna

AU - Saieva, Calogero

AU - Panico, Salvatore

AU - Mattiello, Amalia

AU - Chiodini, Paolo

AU - Tumino, Rosario

AU - Frasca, Graziella

AU - Iacoviello, Licia

AU - de Curtis, Amalia

AU - Vineis, Paolo

AU - Krogh, Vittorio

PY - 2015/5/6

Y1 - 2015/5/6

N2 - Background: The relationship between coffee consumption and coronary heart disease (CHD) has been investigated in several studies with discrepant results. We examined the association between Italian-style (espresso and mocha) coffee consumption and CHD risk. Methods: We investigated 12,800 men and 30,449 women without history of cardiovascular disease recruited to the EPICOR prospective cohort study. Coffee consumption was assessed at baseline. In a random sub-cohort of 1472 subjects, plasma triglycerides, and total, LDL and HDL cholesterol were determined to investigate the effect of coffee consumption on plasma lipids. Results: After a mean follow up of 10.9 years, 804 cases of CHD (500 acute events, 56 fatal events and 248 revascularizations, all first events) were identified. Multivariable adjusted hazard ratios for CHD were: 1.18 (95% CI 0.87-1.60) for drinking 1- 2 cups/day, 1.37 (95% CI 1.03-1.82) for >2-4 cups/day and 1.52 (95% CI 1.11-2.07) for over 4 cups/day (P trend >0.001) compared to reference (>1 cup/day). Plasma triglycerides, and total, LDL and HDL cholesterol did not vary significantly (ANOVA) with coffee consumption.

AB - Background: The relationship between coffee consumption and coronary heart disease (CHD) has been investigated in several studies with discrepant results. We examined the association between Italian-style (espresso and mocha) coffee consumption and CHD risk. Methods: We investigated 12,800 men and 30,449 women without history of cardiovascular disease recruited to the EPICOR prospective cohort study. Coffee consumption was assessed at baseline. In a random sub-cohort of 1472 subjects, plasma triglycerides, and total, LDL and HDL cholesterol were determined to investigate the effect of coffee consumption on plasma lipids. Results: After a mean follow up of 10.9 years, 804 cases of CHD (500 acute events, 56 fatal events and 248 revascularizations, all first events) were identified. Multivariable adjusted hazard ratios for CHD were: 1.18 (95% CI 0.87-1.60) for drinking 1- 2 cups/day, 1.37 (95% CI 1.03-1.82) for >2-4 cups/day and 1.52 (95% CI 1.11-2.07) for over 4 cups/day (P trend >0.001) compared to reference (>1 cup/day). Plasma triglycerides, and total, LDL and HDL cholesterol did not vary significantly (ANOVA) with coffee consumption.

UR - http://www.scopus.com/inward/record.url?scp=84929180024&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929180024&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0126550

DO - 10.1371/journal.pone.0126550

M3 - Article

AN - SCOPUS:84929180024

VL - 10

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 5

M1 - e0126550

ER -