Abstract
To optimize chronic migraine (CM) ascertainment and phenotype definition, provide adequate clinical management and health care procedures, and rationalize economic resources allocation, we performed an exploratory multicenter pilot study aimed at establishing a CM database, the first step for developing a future Italian CM registry. We enrolled 63 consecutive CM patients in four tertiary headache centers screened with face-to-face interviews using an ad hoc dedicated semi-structured questionnaire gathering detailed information on life-style, behavioral and socio-demographic factors, comorbidities, and migraine features before and after chronicization and healthcare resource use. Our pilot study provided useful insights revealing that CM patients (1) presented in most cases symptoms of peripheral trigeminal sensitization, a relatively unexpected feature which could be useful to unravel different CM endophenotypes and to predict trigeminal-targeted treatments’ responsiveness; (2) had been frequently admitted to emergency departments; (3) had undergone, sometime repeatedly, unnecessary or inappropriate investigations; (4) got rarely illness benefit exemption or disability allowance only. We deem that the expansion of the database—shortly including many other Italian headache centers—will contribute to more precisely outline CM endophenotypes, hence improving management, treatment, and economic resource allocation, ultimately reducing CM burden on both patients and health system.
| Original language | English |
|---|---|
| Pages (from-to) | 933-937 |
| Number of pages | 5 |
| Journal | Neurological Sciences |
| Volume | 39 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2018 |
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Keywords
- Chronic migraine
- Database
- Disability
- Epidemiology
- Migraine burden
- Registry
ASJC Scopus subject areas
- Dermatology
- Clinical Neurology
- Psychiatry and Mental health
Cite this
Establishment of an Italian chronic migraine database : a multicenter pilot study. / Barbanti, Piero; Fofi, L.; Cevoli, S.; Torelli, P.; Aurilia, C.; Egeo, G.; Grazzi, L.; D’Amico, D.; Manzoni, G. C.; Cortelli, P.; Infarinato, F.; Vanacore, N.
In: Neurological Sciences, Vol. 39, No. 5, 01.05.2018, p. 933-937.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Establishment of an Italian chronic migraine database
T2 - a multicenter pilot study
AU - Barbanti, Piero
AU - Fofi, L.
AU - Cevoli, S.
AU - Torelli, P.
AU - Aurilia, C.
AU - Egeo, G.
AU - Grazzi, L.
AU - D’Amico, D.
AU - Manzoni, G. C.
AU - Cortelli, P.
AU - Infarinato, F.
AU - Vanacore, N.
PY - 2018/5/1
Y1 - 2018/5/1
N2 - To optimize chronic migraine (CM) ascertainment and phenotype definition, provide adequate clinical management and health care procedures, and rationalize economic resources allocation, we performed an exploratory multicenter pilot study aimed at establishing a CM database, the first step for developing a future Italian CM registry. We enrolled 63 consecutive CM patients in four tertiary headache centers screened with face-to-face interviews using an ad hoc dedicated semi-structured questionnaire gathering detailed information on life-style, behavioral and socio-demographic factors, comorbidities, and migraine features before and after chronicization and healthcare resource use. Our pilot study provided useful insights revealing that CM patients (1) presented in most cases symptoms of peripheral trigeminal sensitization, a relatively unexpected feature which could be useful to unravel different CM endophenotypes and to predict trigeminal-targeted treatments’ responsiveness; (2) had been frequently admitted to emergency departments; (3) had undergone, sometime repeatedly, unnecessary or inappropriate investigations; (4) got rarely illness benefit exemption or disability allowance only. We deem that the expansion of the database—shortly including many other Italian headache centers—will contribute to more precisely outline CM endophenotypes, hence improving management, treatment, and economic resource allocation, ultimately reducing CM burden on both patients and health system.
AB - To optimize chronic migraine (CM) ascertainment and phenotype definition, provide adequate clinical management and health care procedures, and rationalize economic resources allocation, we performed an exploratory multicenter pilot study aimed at establishing a CM database, the first step for developing a future Italian CM registry. We enrolled 63 consecutive CM patients in four tertiary headache centers screened with face-to-face interviews using an ad hoc dedicated semi-structured questionnaire gathering detailed information on life-style, behavioral and socio-demographic factors, comorbidities, and migraine features before and after chronicization and healthcare resource use. Our pilot study provided useful insights revealing that CM patients (1) presented in most cases symptoms of peripheral trigeminal sensitization, a relatively unexpected feature which could be useful to unravel different CM endophenotypes and to predict trigeminal-targeted treatments’ responsiveness; (2) had been frequently admitted to emergency departments; (3) had undergone, sometime repeatedly, unnecessary or inappropriate investigations; (4) got rarely illness benefit exemption or disability allowance only. We deem that the expansion of the database—shortly including many other Italian headache centers—will contribute to more precisely outline CM endophenotypes, hence improving management, treatment, and economic resource allocation, ultimately reducing CM burden on both patients and health system.
KW - Chronic migraine
KW - Database
KW - Disability
KW - Epidemiology
KW - Migraine burden
KW - Registry
UR - http://www.scopus.com/inward/record.url?scp=85042216590&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042216590&partnerID=8YFLogxK
U2 - 10.1007/s10072-018-3280-y
DO - 10.1007/s10072-018-3280-y
M3 - Article
C2 - 29468419
AN - SCOPUS:85042216590
VL - 39
SP - 933
EP - 937
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 5
ER -