Abstract
The esterasic capacity of a series of skeletal muscles in response to three hemisuccinate ester drugs was investigated in rats and compared to that on alpha-naphthylacetate as a reference esterase substrate. Marked variations between different muscles and between given muscles of animals of different sex were observed, indicative of a complex heterogeneity in muscular expression of esterase activity.
| Original language | English |
|---|---|
| Pages (from-to) | 175-177 |
| Number of pages | 3 |
| Journal | European Journal of Drug Metabolism and Pharmacokinetics |
| Volume | 4 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jul 1979 |
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Keywords
- Esterases
- Heterogenicity
- Skeletal muscles
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Esterase activity of rat muscle. / Crespi, F.; Pagliacci, E.; Rocchini, G. M.; Bianchi, R.; Salmona, M.; Garattini, S.; Mussini, E.
In: European Journal of Drug Metabolism and Pharmacokinetics, Vol. 4, No. 3, 07.1979, p. 175-177.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Esterase activity of rat muscle
AU - Crespi, F.
AU - Pagliacci, E.
AU - Rocchini, G. M.
AU - Bianchi, R.
AU - Salmona, M.
AU - Garattini, S.
AU - Mussini, E.
PY - 1979/7
Y1 - 1979/7
N2 - The esterasic capacity of a series of skeletal muscles in response to three hemisuccinate ester drugs was investigated in rats and compared to that on alpha-naphthylacetate as a reference esterase substrate. Marked variations between different muscles and between given muscles of animals of different sex were observed, indicative of a complex heterogeneity in muscular expression of esterase activity.
AB - The esterasic capacity of a series of skeletal muscles in response to three hemisuccinate ester drugs was investigated in rats and compared to that on alpha-naphthylacetate as a reference esterase substrate. Marked variations between different muscles and between given muscles of animals of different sex were observed, indicative of a complex heterogeneity in muscular expression of esterase activity.
KW - Esterases
KW - Heterogenicity
KW - Skeletal muscles
UR - http://www.scopus.com/inward/record.url?scp=0018575547&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018575547&partnerID=8YFLogxK
U2 - 10.1007/BF03189421
DO - 10.1007/BF03189421
M3 - Article
C2 - 527602
AN - SCOPUS:0018575547
VL - 4
SP - 175
EP - 177
JO - European Journal of Drug Metabolism and Pharmacokinetics
JF - European Journal of Drug Metabolism and Pharmacokinetics
SN - 0378-7966
IS - 3
ER -