Abstract
The esterasic capacity of a series of skeletal muscles in response to three hemisuccinate ester drugs was investigated in rats and compared to that on alpha-naphthylacetate as a reference esterase substrate. Marked variations between different muscles and between given muscles of animals of different sex were observed, indicative of a complex heterogeneity in muscular expression of esterase activity.
Original language | English |
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Pages (from-to) | 175-177 |
Number of pages | 3 |
Journal | European Journal of Drug Metabolism and Pharmacokinetics |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jul 1979 |
Keywords
- Esterases
- Heterogenicity
- Skeletal muscles
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)