Abstract
Background: Patients older than 85 years are increasingly admitted to hospital care settings. Despite this, the clinical employment of equations for estimating glomerular filtration rate (GFR) has been scarcely investigated so far in this age group. Our study compared 2 commonly employed equations to estimate GFR, as well as measured 24-hour creatinine clearance (CrCl), in patients aged ≥85 years. Methods: Seventy-three patients consecutively admitted over 4 months to our Internal Medicine Department had an accurate 24-hour urinary collection, as well as serum and urinary creatinine determinations. Measured CrCl was compared with the GFR values estimated by the Modification of Diet in Renal Disease (MDRD) Study and Mayo Clinic quadratic (MCQ) equations. Results: GFR values derived by MDRD and MCQ equations and CrCl significantly differed from each other in the whole sample. CrCl negatively correlated with age (r=-0.389, p
| Original language | English |
|---|---|
| Pages (from-to) | 306-313 |
| Number of pages | 8 |
| Journal | Journal of Nephrology |
| Volume | 23 |
| Issue number | 3 |
| Publication status | Published - May 2010 |
Fingerprint
Keywords
- 24-Hour creatinine clearance
- Mayo Clinic quadratic equation
- MDRD equation
- Oldest old inpatients
ASJC Scopus subject areas
- Nephrology
Cite this
Estimate of renal function in oldest old inpatients by MDRD study equation, Mayo Clinic equation and creatinine clearance. / Carnevale, Vincenzo; Pastore, Luca; Camaioni, Marcello; Mellozzi, Monica; Sabatini, Massimo; Arietti, Elisabetta; Fusilli, Saverio; Scillitani, Alfredo; Pontecorvi, Mario.
In: Journal of Nephrology, Vol. 23, No. 3, 05.2010, p. 306-313.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Estimate of renal function in oldest old inpatients by MDRD study equation, Mayo Clinic equation and creatinine clearance
AU - Carnevale, Vincenzo
AU - Pastore, Luca
AU - Camaioni, Marcello
AU - Mellozzi, Monica
AU - Sabatini, Massimo
AU - Arietti, Elisabetta
AU - Fusilli, Saverio
AU - Scillitani, Alfredo
AU - Pontecorvi, Mario
PY - 2010/5
Y1 - 2010/5
N2 - Background: Patients older than 85 years are increasingly admitted to hospital care settings. Despite this, the clinical employment of equations for estimating glomerular filtration rate (GFR) has been scarcely investigated so far in this age group. Our study compared 2 commonly employed equations to estimate GFR, as well as measured 24-hour creatinine clearance (CrCl), in patients aged ≥85 years. Methods: Seventy-three patients consecutively admitted over 4 months to our Internal Medicine Department had an accurate 24-hour urinary collection, as well as serum and urinary creatinine determinations. Measured CrCl was compared with the GFR values estimated by the Modification of Diet in Renal Disease (MDRD) Study and Mayo Clinic quadratic (MCQ) equations. Results: GFR values derived by MDRD and MCQ equations and CrCl significantly differed from each other in the whole sample. CrCl negatively correlated with age (r=-0.389, p
AB - Background: Patients older than 85 years are increasingly admitted to hospital care settings. Despite this, the clinical employment of equations for estimating glomerular filtration rate (GFR) has been scarcely investigated so far in this age group. Our study compared 2 commonly employed equations to estimate GFR, as well as measured 24-hour creatinine clearance (CrCl), in patients aged ≥85 years. Methods: Seventy-three patients consecutively admitted over 4 months to our Internal Medicine Department had an accurate 24-hour urinary collection, as well as serum and urinary creatinine determinations. Measured CrCl was compared with the GFR values estimated by the Modification of Diet in Renal Disease (MDRD) Study and Mayo Clinic quadratic (MCQ) equations. Results: GFR values derived by MDRD and MCQ equations and CrCl significantly differed from each other in the whole sample. CrCl negatively correlated with age (r=-0.389, p
KW - 24-Hour creatinine clearance
KW - Mayo Clinic quadratic equation
KW - MDRD equation
KW - Oldest old inpatients
UR - http://www.scopus.com/inward/record.url?scp=77951729268&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951729268&partnerID=8YFLogxK
M3 - Article
C2 - 20155719
AN - SCOPUS:77951729268
VL - 23
SP - 306
EP - 313
JO - Journal of Nephrology
JF - Journal of Nephrology
SN - 1121-8428
IS - 3
ER -