Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort

Raul Zamora-Ros, Viktoria Knaze, Leila Luján-Barroso, Nadia Slimani, Isabelle Romieu, Veronika Fedirko, Maria Santucci De Magistris, Ulrica Ericson, Pilar Amiano, Antonia Trichopoulou, Vardis Dilis, Androniki Naska, Dagrun Engeset, Guri Skeie, Aedin Cassidy, Kim Overvad, Petra H M Peeters, José María Huerta, María José Sánchez, J. Ramón QuirósCarlotta Sacerdote, Sara Grioni, Rosario Tumino, Gerd Johansson, Ingegerd Johansson, Isabel Drake, Francesca L. Crowe, Aurelio Barricarte, Rudolf Kaaks, Birgit Teucher, H. Bas Bueno-De-Mesquita, Caroline T M Van Rossum, Teresa Norat, Dora Romaguera, Anne Claire Vergnaud, Anne Tjønneland, Jytte Halkjær, Françoise Clavel-Chapelon, Marie Christine Boutron-Ruault, Marina Touillaud, Simonetta Salvini, Kay Thee Khaw, Nicholas Wareham, Heiner Boeing, Jana Förster, Elio Riboli, Carlos A. González

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Flavonols, flavanones and flavones (FLAV) are sub-classes of flavonoids that exert cardioprotective and anti-carcinogenic properties in vitro and in vivo. We aimed to estimate the FLAV dietary intake, their food sources and associated lifestyle factors in ten European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. FLAV intake and their food sources for 36037 subjects, aged between 35 and 74 years, in twenty-seven study centres were obtained using standardised 24h dietary recall software (EPIC-SOFT). An ad hoc food composition database on FLAV was compiled using data from US Department of Agriculture and Phenol-Explorer databases and was expanded using recipes, estimations and flavonoid retention factors in order to increase its correspondence with the 24h dietary recall. Our results showed that the highest FLAV-consuming centre was the UK health-conscious group, with 130.9 and 97.0mg/d for men and women, respectively. The lowest FLAV intakes were 36.8mg/d in men from Umea° and 37.2mg/d in women from Malmö (Sweden). The flavanone sub-class was the main contributor to the total FLAV intake ranging from 46.6 to 52.9% depending on the region. Flavonols ranged from 38.5 to 47.3% and flavones from 5.8 to 8.6%. FLAV intake was higher in women, non-smokers, increased with level of education and physical activity. The major food sources were citrus fruits and citrus-based juices (especially for flavanones), tea, wine, other fruits and some vegetables. We concluded that the present study shows heterogeneity in intake of these three sub-classes of flavonoids across European regions and highlights differences by sex and other sociodemographic and lifestyle factors.

Original languageEnglish
Pages (from-to)1915-1925
Number of pages11
JournalBritish Journal of Nutrition
Volume106
Issue number12
DOIs
Publication statusPublished - Dec 28 2011

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Flavanones
Flavones
Flavonols
Neoplasms
Flavonoids
Citrus
Life Style
Eating
Databases
Food
United States Department of Agriculture
Tea
Wine
Phenol
Sweden
Sex Characteristics
Vegetables
Fruit
Software
Exercise

Keywords

  • EPIC-Europe
  • Flavanones
  • Flavones
  • Flavonols

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort. / Zamora-Ros, Raul; Knaze, Viktoria; Luján-Barroso, Leila; Slimani, Nadia; Romieu, Isabelle; Fedirko, Veronika; Santucci De Magistris, Maria; Ericson, Ulrica; Amiano, Pilar; Trichopoulou, Antonia; Dilis, Vardis; Naska, Androniki; Engeset, Dagrun; Skeie, Guri; Cassidy, Aedin; Overvad, Kim; Peeters, Petra H M; María Huerta, José; Sánchez, María José; Quirós, J. Ramón; Sacerdote, Carlotta; Grioni, Sara; Tumino, Rosario; Johansson, Gerd; Johansson, Ingegerd; Drake, Isabel; Crowe, Francesca L.; Barricarte, Aurelio; Kaaks, Rudolf; Teucher, Birgit; Bas Bueno-De-Mesquita, H.; Van Rossum, Caroline T M; Norat, Teresa; Romaguera, Dora; Vergnaud, Anne Claire; Tjønneland, Anne; Halkjær, Jytte; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Touillaud, Marina; Salvini, Simonetta; Khaw, Kay Thee; Wareham, Nicholas; Boeing, Heiner; Förster, Jana; Riboli, Elio; González, Carlos A.

In: British Journal of Nutrition, Vol. 106, No. 12, 28.12.2011, p. 1915-1925.

Research output: Contribution to journalArticle

Zamora-Ros, R, Knaze, V, Luján-Barroso, L, Slimani, N, Romieu, I, Fedirko, V, Santucci De Magistris, M, Ericson, U, Amiano, P, Trichopoulou, A, Dilis, V, Naska, A, Engeset, D, Skeie, G, Cassidy, A, Overvad, K, Peeters, PHM, María Huerta, J, Sánchez, MJ, Quirós, JR, Sacerdote, C, Grioni, S, Tumino, R, Johansson, G, Johansson, I, Drake, I, Crowe, FL, Barricarte, A, Kaaks, R, Teucher, B, Bas Bueno-De-Mesquita, H, Van Rossum, CTM, Norat, T, Romaguera, D, Vergnaud, AC, Tjønneland, A, Halkjær, J, Clavel-Chapelon, F, Boutron-Ruault, MC, Touillaud, M, Salvini, S, Khaw, KT, Wareham, N, Boeing, H, Förster, J, Riboli, E & González, CA 2011, 'Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort', British Journal of Nutrition, vol. 106, no. 12, pp. 1915-1925. https://doi.org/10.1017/S000711451100239X
Zamora-Ros, Raul ; Knaze, Viktoria ; Luján-Barroso, Leila ; Slimani, Nadia ; Romieu, Isabelle ; Fedirko, Veronika ; Santucci De Magistris, Maria ; Ericson, Ulrica ; Amiano, Pilar ; Trichopoulou, Antonia ; Dilis, Vardis ; Naska, Androniki ; Engeset, Dagrun ; Skeie, Guri ; Cassidy, Aedin ; Overvad, Kim ; Peeters, Petra H M ; María Huerta, José ; Sánchez, María José ; Quirós, J. Ramón ; Sacerdote, Carlotta ; Grioni, Sara ; Tumino, Rosario ; Johansson, Gerd ; Johansson, Ingegerd ; Drake, Isabel ; Crowe, Francesca L. ; Barricarte, Aurelio ; Kaaks, Rudolf ; Teucher, Birgit ; Bas Bueno-De-Mesquita, H. ; Van Rossum, Caroline T M ; Norat, Teresa ; Romaguera, Dora ; Vergnaud, Anne Claire ; Tjønneland, Anne ; Halkjær, Jytte ; Clavel-Chapelon, Françoise ; Boutron-Ruault, Marie Christine ; Touillaud, Marina ; Salvini, Simonetta ; Khaw, Kay Thee ; Wareham, Nicholas ; Boeing, Heiner ; Förster, Jana ; Riboli, Elio ; González, Carlos A. / Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort. In: British Journal of Nutrition. 2011 ; Vol. 106, No. 12. pp. 1915-1925.
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abstract = "Flavonols, flavanones and flavones (FLAV) are sub-classes of flavonoids that exert cardioprotective and anti-carcinogenic properties in vitro and in vivo. We aimed to estimate the FLAV dietary intake, their food sources and associated lifestyle factors in ten European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. FLAV intake and their food sources for 36037 subjects, aged between 35 and 74 years, in twenty-seven study centres were obtained using standardised 24h dietary recall software (EPIC-SOFT). An ad hoc food composition database on FLAV was compiled using data from US Department of Agriculture and Phenol-Explorer databases and was expanded using recipes, estimations and flavonoid retention factors in order to increase its correspondence with the 24h dietary recall. Our results showed that the highest FLAV-consuming centre was the UK health-conscious group, with 130.9 and 97.0mg/d for men and women, respectively. The lowest FLAV intakes were 36.8mg/d in men from Umea° and 37.2mg/d in women from Malm{\"o} (Sweden). The flavanone sub-class was the main contributor to the total FLAV intake ranging from 46.6 to 52.9{\%} depending on the region. Flavonols ranged from 38.5 to 47.3{\%} and flavones from 5.8 to 8.6{\%}. FLAV intake was higher in women, non-smokers, increased with level of education and physical activity. The major food sources were citrus fruits and citrus-based juices (especially for flavanones), tea, wine, other fruits and some vegetables. We concluded that the present study shows heterogeneity in intake of these three sub-classes of flavonoids across European regions and highlights differences by sex and other sociodemographic and lifestyle factors.",
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T1 - Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort

AU - Zamora-Ros, Raul

AU - Knaze, Viktoria

AU - Luján-Barroso, Leila

AU - Slimani, Nadia

AU - Romieu, Isabelle

AU - Fedirko, Veronika

AU - Santucci De Magistris, Maria

AU - Ericson, Ulrica

AU - Amiano, Pilar

AU - Trichopoulou, Antonia

AU - Dilis, Vardis

AU - Naska, Androniki

AU - Engeset, Dagrun

AU - Skeie, Guri

AU - Cassidy, Aedin

AU - Overvad, Kim

AU - Peeters, Petra H M

AU - María Huerta, José

AU - Sánchez, María José

AU - Quirós, J. Ramón

AU - Sacerdote, Carlotta

AU - Grioni, Sara

AU - Tumino, Rosario

AU - Johansson, Gerd

AU - Johansson, Ingegerd

AU - Drake, Isabel

AU - Crowe, Francesca L.

AU - Barricarte, Aurelio

AU - Kaaks, Rudolf

AU - Teucher, Birgit

AU - Bas Bueno-De-Mesquita, H.

AU - Van Rossum, Caroline T M

AU - Norat, Teresa

AU - Romaguera, Dora

AU - Vergnaud, Anne Claire

AU - Tjønneland, Anne

AU - Halkjær, Jytte

AU - Clavel-Chapelon, Françoise

AU - Boutron-Ruault, Marie Christine

AU - Touillaud, Marina

AU - Salvini, Simonetta

AU - Khaw, Kay Thee

AU - Wareham, Nicholas

AU - Boeing, Heiner

AU - Förster, Jana

AU - Riboli, Elio

AU - González, Carlos A.

PY - 2011/12/28

Y1 - 2011/12/28

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