Abstract
Morning blood pressure (BP) surge has been reported to be a prognostic factor for cardiovascular events. Its determinants are still poorly defined, however. In particular, it is not clear whether ethnic differences play a role in determining morning surge (MS) size. Aim of our study was to explore whether differences exist in the size of MS between Japanese and Western European hypertensive patients. We included 2887 untreated hypertensive patients (age 62.3±8.8 years) from a European ambulatory BP monitoring database and 811 hypertensive patients from a Japanese database (Jichi Medical School Ambulatory Blood Pressure Monitoring WAVE1, age 72.3±9.8 years) following the same inclusion criteria. Their 24-hour ambulatory BP monitoring recordings were analyzed focusing on MS. Sleep-trough MS was defined as the difference between mean systolic BP during the 2 hours after awakening and mean systolic BP during the 1-hour night period that included the lowest sleep BP level. The sleep-trough MS was higher in Japanese than in European hypertensive patients after adjusting for age and 24-hour mean BP levels (40.1 [95% confidence interval 39.0-41.2] versus 23.0 [22.4-23.5] mm Hg; P
| Original language | English |
|---|---|
| Pages (from-to) | 750-756 |
| Number of pages | 7 |
| Journal | Hypertension |
| Volume | 66 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 11 2015 |
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Keywords
- ambulatory blood pressure monitoring
- arterial hypertension
- blood pressure variability
- cardiovascular events
- ethnicity
- morning blood pressure surge
- sympathetic nervous system
ASJC Scopus subject areas
- Internal Medicine
- Medicine(all)
Cite this
Ethnic differences in the degree of morning blood pressure surge and in its determinants between Japanese and european hypertensive subjects : Data from the ARTEMIS study. / Hoshide, Satoshi; Kario, Kazuomi; De La Sierra, Alejandro; Bilo, Grzegorz; Schillaci, Giuseppe; Banegas, José Ramón; Gorostidi, Manuel; Segura, Julian; Lombardi, Carolina; Omboni, Stefano; Ruilope, Luis; Mancia, Giuseppe; Parati, Gianfranco.
In: Hypertension, Vol. 66, No. 4, 11.10.2015, p. 750-756.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ethnic differences in the degree of morning blood pressure surge and in its determinants between Japanese and european hypertensive subjects
T2 - Data from the ARTEMIS study
AU - Hoshide, Satoshi
AU - Kario, Kazuomi
AU - De La Sierra, Alejandro
AU - Bilo, Grzegorz
AU - Schillaci, Giuseppe
AU - Banegas, José Ramón
AU - Gorostidi, Manuel
AU - Segura, Julian
AU - Lombardi, Carolina
AU - Omboni, Stefano
AU - Ruilope, Luis
AU - Mancia, Giuseppe
AU - Parati, Gianfranco
PY - 2015/10/11
Y1 - 2015/10/11
N2 - Morning blood pressure (BP) surge has been reported to be a prognostic factor for cardiovascular events. Its determinants are still poorly defined, however. In particular, it is not clear whether ethnic differences play a role in determining morning surge (MS) size. Aim of our study was to explore whether differences exist in the size of MS between Japanese and Western European hypertensive patients. We included 2887 untreated hypertensive patients (age 62.3±8.8 years) from a European ambulatory BP monitoring database and 811 hypertensive patients from a Japanese database (Jichi Medical School Ambulatory Blood Pressure Monitoring WAVE1, age 72.3±9.8 years) following the same inclusion criteria. Their 24-hour ambulatory BP monitoring recordings were analyzed focusing on MS. Sleep-trough MS was defined as the difference between mean systolic BP during the 2 hours after awakening and mean systolic BP during the 1-hour night period that included the lowest sleep BP level. The sleep-trough MS was higher in Japanese than in European hypertensive patients after adjusting for age and 24-hour mean BP levels (40.1 [95% confidence interval 39.0-41.2] versus 23.0 [22.4-23.5] mm Hg; P
AB - Morning blood pressure (BP) surge has been reported to be a prognostic factor for cardiovascular events. Its determinants are still poorly defined, however. In particular, it is not clear whether ethnic differences play a role in determining morning surge (MS) size. Aim of our study was to explore whether differences exist in the size of MS between Japanese and Western European hypertensive patients. We included 2887 untreated hypertensive patients (age 62.3±8.8 years) from a European ambulatory BP monitoring database and 811 hypertensive patients from a Japanese database (Jichi Medical School Ambulatory Blood Pressure Monitoring WAVE1, age 72.3±9.8 years) following the same inclusion criteria. Their 24-hour ambulatory BP monitoring recordings were analyzed focusing on MS. Sleep-trough MS was defined as the difference between mean systolic BP during the 2 hours after awakening and mean systolic BP during the 1-hour night period that included the lowest sleep BP level. The sleep-trough MS was higher in Japanese than in European hypertensive patients after adjusting for age and 24-hour mean BP levels (40.1 [95% confidence interval 39.0-41.2] versus 23.0 [22.4-23.5] mm Hg; P
KW - ambulatory blood pressure monitoring
KW - arterial hypertension
KW - blood pressure variability
KW - cardiovascular events
KW - ethnicity
KW - morning blood pressure surge
KW - sympathetic nervous system
UR - http://www.scopus.com/inward/record.url?scp=84941215072&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941215072&partnerID=8YFLogxK
U2 - 10.1161/HYPERTENSIONAHA.115.05958
DO - 10.1161/HYPERTENSIONAHA.115.05958
M3 - Article
C2 - 26303289
AN - SCOPUS:84941215072
VL - 66
SP - 750
EP - 756
JO - Hypertension
JF - Hypertension
SN - 0194-911X
IS - 4
ER -