Research output: Chapter in Book/Report/Conference proceedingChapter


Experimental models of the disease, as experimental allergic encephalitis (EAE), a virus-induced demyelination, and several clinical and laboratory data suggest that MS is a multifactorial disease in which one or more environmental factors contribute to trigger an immune response directed against myelin antigens in genetically susceptible subjects. From a pathogenic point of view it is important to consider: genetic, viral and immunological factors. Recently many researchers cast doubt on the classification of MS as an autoimmune disease suggesting that a chronic cerebrospinal venous insufficiency (CCSVI) plays a role in the cause of MS.

Original languageEnglish
Title of host publicationNeuropsychiatric Dysfunction in Multiple Sclerosis
PublisherSpringer-Verlag Italia s.r.l.
Number of pages5
ISBN (Print)9788847026766, 884702675X, 9788847026759
Publication statusPublished - May 1 2012

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Etiopathogenesis'. Together they form a unique fingerprint.

Cite this