Fifty patients with advanced squamous cell carcinoma and adenocarcinoma of the lung having good prognostic features (performance status ≤ 2; weight loss ≤ 10%; and age ≤ 70 years; absence of brain metastases; and no prior treatment) were treated on an outpatient basis with etoposide (120 mg/m2 on Days 1, 3, and 5) and cisplatin (60 mg/m2 on Days 1 and 2) every 21-28 days. One complete response and 14 partial responses were observed, with a median duration of response of 170 days and an overall median survival of 230 days. Toxicity was generally mild. Despite the high-dose cisplatin employed and the choice of patients with favorable prognostic factors in this study, results of this therapy remain disappointing.
|Number of pages||2|
|Journal||Cancer Treatment Reports|
|Publication status||Published - 1986|
ASJC Scopus subject areas
- Cancer Research