EU pancreas: An integrated european platform for pancreas cancer research - From basic science to clinical and public health interventions for a rare disease

R. Milne, C. La Vecchia, K. Van Steen, S. Hahn, M. Buchholz, E. Costello, I. Esposito, J. D. Hoheisel, B. Lange, N. Lopez-Bigas, C. W. Michalski, F. X. Real, A. Brand, N. Malats, Núria Malats, Carlo LaVecchia, Kristel Van Steen, Drazenka Macic, Timur Ceric, Juan IovannaStephan Hahn, Jorg Kleeff, Maria Gazouli, Christos Dervenis, Peter Hegyi, Ralph Ruhl, Amir Shafat, Linda Sharp, Anwar Rayan, Adriano DeCarli, Giampolo Tortora, Audrius Sileikis, Giedrius Barauskas, Sonja Eriksson Steigen, Tone Ikdahl, Ewa Malecka-Panas, Filipe Santos Silva, Traian Sorin Barbu, Irinel Popescu, Maria Durisova, Magdalena Majekova, Vita Dolzan, Lutfi Genc, Hatice Yildirim, Tajana Crnogorac-Jurcevic, Angela Brand, Roger Milne, Eithne Costello, Malte Bulchholz, Carlo La Vecchia, Bill Greenhalf, Fiona Campbell, Gunter Kloeppel, Bas Bueno De Mesquita, Jorg Hoheisel, Alvis Brazma, Raph Herwig, Eric Van Cutsum, Darlene Goldstein, Ewan Birney, Claudio Bassi, Andrew Biankin, Aldo Scarpa, Christoph Michalski, Marlène Dufresne, Claude Chelala, Hermant Kocher, Ewout Steyerberg, Daniela Cecconi, Matthias Löhr, Inaki Gutierrez- Ibarluzea, Roza Adany, Denis Horgan, Domenica Taruscio, Bonnie Wolff-Boehnisch, Hans Peter Dauben, Rósa Björk Barbardorttir, Ilias Papadopoulos, Philippe Callens, Ivana Holcatova, Hermann Brenner, Daniele Campa, Federico Canzian, Cosmeri Rizzato, Jutta Lüttges, Thomas Gress, Detlef Bartch, Tonia Vlahou, Cristina Fillat, Mònica Bayés, Ivo Gut, Marta Gut, Magda Gasull, Víctor Barberá, Miquel Porta, Xavier Molero, Eric Duell, Eduardo Ález-Couto, Alfredo Carrato, Carmen Guillén, Paola Martinelli, Manuel Hidalgo, Christopher Heeschen, Alfonso Valencia, Ma Luz Calle, Roderic Guigó, Ghislaine Scelo, Paolo Boffetta, Patrick Maisonneuve, Cristina Bosetti, Ersilia Lucenteforte, Suzanne Jeurnink, Franzel Van Duijnhoven, Witold Zatonski, Ljiljana Petronijevic, Caroline Verbeke, John Neoptolemos

Research output: Contribution to journalArticle

Abstract

Background: Large-scale international collaboration is essential to decipher relevant information in the context of omics-scale interrogations in cancer research. This is even more important for rare and fatal diseases like pancreas cancer (PC). Methods: The COST Action BM1204 is a unique platform to facilitate the collaboration of a broad range of European and international PC multidisciplinary research groups in order to: (1) integrate knowledge and experience in a multidisciplinary way 'from cell to society', (2) promote the application of uniform study tools and protocols, (3) foster their optimal use by early-stage researchers, (4) enhance the mobility and training of researchers, and (5) disseminate the results produced to the broader society. Results: This Action will develop novel interdisciplinary tools for collaborative research to improve our understanding of PC and its prevention, diagnosis and treatment. It also aims to answer questions related to the etiology, early detection, evidence-based and personalized treatment, and health management for PC. Furthermore, the Action will contribute to new insights into PC personalized medicine and beyond as well as to the understanding of complex and rare diseases taking PC as a best practice example. The Action aims at attracting young scholars across a range of disciplines in collaboration with more experienced researchers and enhancing active European participation in the international scenario of PC research. Conclusion: The ultimate aim is to foster PC research in Europe and to coordinate this effort with other international initiatives to reduce disease mortality.

Original languageEnglish
Pages (from-to)305-312
Number of pages8
JournalPublic Health Genomics
Volume16
Issue number6
DOIs
Publication statusPublished - Apr 20 2013

Keywords

  • COST Action BM1204
  • Data integration
  • Early-stage researchers
  • Harmonization
  • Omics data
  • Pancreas cancer
  • Public health
  • Rare disease
  • Training and mobility

ASJC Scopus subject areas

  • Genetics(clinical)
  • Public Health, Environmental and Occupational Health

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  • Cite this

    Milne, R., La Vecchia, C., Van Steen, K., Hahn, S., Buchholz, M., Costello, E., Esposito, I., Hoheisel, J. D., Lange, B., Lopez-Bigas, N., Michalski, C. W., Real, F. X., Brand, A., Malats, N., Malats, N., LaVecchia, C., Van Steen, K., Macic, D., Ceric, T., ... Neoptolemos, J. (2013). EU pancreas: An integrated european platform for pancreas cancer research - From basic science to clinical and public health interventions for a rare disease. Public Health Genomics, 16(6), 305-312. https://doi.org/10.1159/000355937