EuroHeart Failure Survey II (EHFS II): A survey on hospitalized acute heart failure patients: Description of population

Markku S. Nieminen, Dirk Brutsaert, Kenneth Dickstein, Helmut Drexler, Ferenc Follath, Veli Pekka Harjola, Matthias Hochadel, Michel Komajda, Johan Lassus, Jose Luis Lopez-Sendon, Piotr Ponikowski, Luigi Tavazzi, Malika Manini, Claire Bramley, Valerie Laforest, Charles Taylor, M. Hochadel, Kurt Huber, Guy De Backer, Vera SirakovaRoman Cerbak, Per Thayssen, Osama Abdel Aziz, Khalid Tammam, Seppo Lehto, François Delahaye, Bondo Kobulia, Uwe Zeymer, Dennis Cokkinos, Dimitrios Krematisnos, Kristof Karlocai, Emer Shelley, Shlomo Behar, Aldo Maggioni, Virginija Grabauskiene, Jaap Deckers, Inger Asmussen, Janina Stepinska, Lino Gonçalves, Vyacheslav Mareev, Zonara Vasilijevic, Igor Riecansky, Miran F. Kenda, Annika Rosengren, Peter Buser, Tugrul Okay, Oleg Sychov, Peter Schofield, Anselm Gitt, G. Rosano, EuroHeart Survey Investigators

Research output: Contribution to journalReview article

747 Citations (Scopus)

Abstract

Aims The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics,aetiology, treatment, and outcome of acute heart failure (AHF) in Europe in relation to the guidelines on the diagnosis and treatment of AHF published by the European Society of Cardiology. Methods and results Patients hospitalized for AHF were recruited by 133 centres in 30 European countries. Three thousand five hundred and eighty patients were entered into the database by the end of August 2005. Mean age was 70 years, and 61% of patients were male. New-onset AHF (de novo AHF) was diagnosed in 37%, of which 42% was due to acute coronary syndromes (ACS). Clinical classification according to the guidelines divided AHF patients into (i) decompensated HF (65%), (ii) pulmonary oedema (16%), (iii) HF and hypertension (11%), (iv) cardiogenic shock (4%), and (v) right HF (3%). Coronary heart disease, hypertension, and atrial fibrillation were the most common underlying conditions. Arrhythmias, valvular dysfunction, and ACS were each present as precipitating factor in one-third of cases. Preserved left ventricular ejection fraction (≥45%) was observed in 34%. Valvular disorders were common, especially mitral regurgitation (MR) which was reported on echocardiography in 80% of patients. Median length of stay was 9 days, and in-hospital mortality 6.7%. At discharge, 80% of patients were on angiotensin-converting enzyme-inhibitors or angiotensin receptor blockers, whereas 61% were taking beta-blocker medication. Conclusion Decompensated HF is the most common clinical presentation of AHF patients. More than one-third of AHF patients do not have a previous history of HF, and new-onset HF is often caused by ACS. Preserved systolic function is found in a substantial proportion of the patients. The prevalence of valvular dysfunction is strikingly high and contributes to the clinical presentation. The EHFS II on AHF verified that the use of evidence-based HF medication was well adopted to clinical practice.

Original languageEnglish
Pages (from-to)2725-2736
Number of pages12
JournalEuropean Heart Journal
Volume27
Issue number22
DOIs
Publication statusPublished - 2006

Fingerprint

Heart Failure
Population
Acute Coronary Syndrome
Surveys and Questionnaires
Guidelines
Hypertension
Precipitating Factors
Cardiogenic Shock
Angiotensin Receptor Antagonists
Mitral Valve Insufficiency
Pulmonary Edema
Hospital Mortality
Angiotensin-Converting Enzyme Inhibitors
Stroke Volume
Atrial Fibrillation
Coronary Disease
Echocardiography
Cardiac Arrhythmias
Length of Stay
Databases

Keywords

  • Acute heart failure
  • Demographics
  • Echocardiography
  • EuroHeart Survey
  • Treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Nieminen, M. S., Brutsaert, D., Dickstein, K., Drexler, H., Follath, F., Harjola, V. P., ... EuroHeart Survey Investigators (2006). EuroHeart Failure Survey II (EHFS II): A survey on hospitalized acute heart failure patients: Description of population. European Heart Journal, 27(22), 2725-2736. https://doi.org/10.1093/eurheartj/ehl193

EuroHeart Failure Survey II (EHFS II) : A survey on hospitalized acute heart failure patients: Description of population. / Nieminen, Markku S.; Brutsaert, Dirk; Dickstein, Kenneth; Drexler, Helmut; Follath, Ferenc; Harjola, Veli Pekka; Hochadel, Matthias; Komajda, Michel; Lassus, Johan; Lopez-Sendon, Jose Luis; Ponikowski, Piotr; Tavazzi, Luigi; Manini, Malika; Bramley, Claire; Laforest, Valerie; Taylor, Charles; Hochadel, M.; Huber, Kurt; De Backer, Guy; Sirakova, Vera; Cerbak, Roman; Thayssen, Per; Abdel Aziz, Osama; Tammam, Khalid; Lehto, Seppo; Delahaye, François; Kobulia, Bondo; Zeymer, Uwe; Cokkinos, Dennis; Krematisnos, Dimitrios; Karlocai, Kristof; Shelley, Emer; Behar, Shlomo; Maggioni, Aldo; Grabauskiene, Virginija; Deckers, Jaap; Asmussen, Inger; Stepinska, Janina; Gonçalves, Lino; Mareev, Vyacheslav; Vasilijevic, Zonara; Riecansky, Igor; Kenda, Miran F.; Rosengren, Annika; Buser, Peter; Okay, Tugrul; Sychov, Oleg; Schofield, Peter; Gitt, Anselm; Rosano, G.; EuroHeart Survey Investigators.

In: European Heart Journal, Vol. 27, No. 22, 2006, p. 2725-2736.

Research output: Contribution to journalReview article

Nieminen, MS, Brutsaert, D, Dickstein, K, Drexler, H, Follath, F, Harjola, VP, Hochadel, M, Komajda, M, Lassus, J, Lopez-Sendon, JL, Ponikowski, P, Tavazzi, L, Manini, M, Bramley, C, Laforest, V, Taylor, C, Hochadel, M, Huber, K, De Backer, G, Sirakova, V, Cerbak, R, Thayssen, P, Abdel Aziz, O, Tammam, K, Lehto, S, Delahaye, F, Kobulia, B, Zeymer, U, Cokkinos, D, Krematisnos, D, Karlocai, K, Shelley, E, Behar, S, Maggioni, A, Grabauskiene, V, Deckers, J, Asmussen, I, Stepinska, J, Gonçalves, L, Mareev, V, Vasilijevic, Z, Riecansky, I, Kenda, MF, Rosengren, A, Buser, P, Okay, T, Sychov, O, Schofield, P, Gitt, A, Rosano, G & EuroHeart Survey Investigators 2006, 'EuroHeart Failure Survey II (EHFS II): A survey on hospitalized acute heart failure patients: Description of population', European Heart Journal, vol. 27, no. 22, pp. 2725-2736. https://doi.org/10.1093/eurheartj/ehl193
Nieminen, Markku S. ; Brutsaert, Dirk ; Dickstein, Kenneth ; Drexler, Helmut ; Follath, Ferenc ; Harjola, Veli Pekka ; Hochadel, Matthias ; Komajda, Michel ; Lassus, Johan ; Lopez-Sendon, Jose Luis ; Ponikowski, Piotr ; Tavazzi, Luigi ; Manini, Malika ; Bramley, Claire ; Laforest, Valerie ; Taylor, Charles ; Hochadel, M. ; Huber, Kurt ; De Backer, Guy ; Sirakova, Vera ; Cerbak, Roman ; Thayssen, Per ; Abdel Aziz, Osama ; Tammam, Khalid ; Lehto, Seppo ; Delahaye, François ; Kobulia, Bondo ; Zeymer, Uwe ; Cokkinos, Dennis ; Krematisnos, Dimitrios ; Karlocai, Kristof ; Shelley, Emer ; Behar, Shlomo ; Maggioni, Aldo ; Grabauskiene, Virginija ; Deckers, Jaap ; Asmussen, Inger ; Stepinska, Janina ; Gonçalves, Lino ; Mareev, Vyacheslav ; Vasilijevic, Zonara ; Riecansky, Igor ; Kenda, Miran F. ; Rosengren, Annika ; Buser, Peter ; Okay, Tugrul ; Sychov, Oleg ; Schofield, Peter ; Gitt, Anselm ; Rosano, G. ; EuroHeart Survey Investigators. / EuroHeart Failure Survey II (EHFS II) : A survey on hospitalized acute heart failure patients: Description of population. In: European Heart Journal. 2006 ; Vol. 27, No. 22. pp. 2725-2736.
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abstract = "Aims The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics,aetiology, treatment, and outcome of acute heart failure (AHF) in Europe in relation to the guidelines on the diagnosis and treatment of AHF published by the European Society of Cardiology. Methods and results Patients hospitalized for AHF were recruited by 133 centres in 30 European countries. Three thousand five hundred and eighty patients were entered into the database by the end of August 2005. Mean age was 70 years, and 61{\%} of patients were male. New-onset AHF (de novo AHF) was diagnosed in 37{\%}, of which 42{\%} was due to acute coronary syndromes (ACS). Clinical classification according to the guidelines divided AHF patients into (i) decompensated HF (65{\%}), (ii) pulmonary oedema (16{\%}), (iii) HF and hypertension (11{\%}), (iv) cardiogenic shock (4{\%}), and (v) right HF (3{\%}). Coronary heart disease, hypertension, and atrial fibrillation were the most common underlying conditions. Arrhythmias, valvular dysfunction, and ACS were each present as precipitating factor in one-third of cases. Preserved left ventricular ejection fraction (≥45{\%}) was observed in 34{\%}. Valvular disorders were common, especially mitral regurgitation (MR) which was reported on echocardiography in 80{\%} of patients. Median length of stay was 9 days, and in-hospital mortality 6.7{\%}. At discharge, 80{\%} of patients were on angiotensin-converting enzyme-inhibitors or angiotensin receptor blockers, whereas 61{\%} were taking beta-blocker medication. Conclusion Decompensated HF is the most common clinical presentation of AHF patients. More than one-third of AHF patients do not have a previous history of HF, and new-onset HF is often caused by ACS. Preserved systolic function is found in a substantial proportion of the patients. The prevalence of valvular dysfunction is strikingly high and contributes to the clinical presentation. The EHFS II on AHF verified that the use of evidence-based HF medication was well adopted to clinical practice.",
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author = "Nieminen, {Markku S.} and Dirk Brutsaert and Kenneth Dickstein and Helmut Drexler and Ferenc Follath and Harjola, {Veli Pekka} and Matthias Hochadel and Michel Komajda and Johan Lassus and Lopez-Sendon, {Jose Luis} and Piotr Ponikowski and Luigi Tavazzi and Malika Manini and Claire Bramley and Valerie Laforest and Charles Taylor and M. Hochadel and Kurt Huber and {De Backer}, Guy and Vera Sirakova and Roman Cerbak and Per Thayssen and {Abdel Aziz}, Osama and Khalid Tammam and Seppo Lehto and Fran{\cc}ois Delahaye and Bondo Kobulia and Uwe Zeymer and Dennis Cokkinos and Dimitrios Krematisnos and Kristof Karlocai and Emer Shelley and Shlomo Behar and Aldo Maggioni and Virginija Grabauskiene and Jaap Deckers and Inger Asmussen and Janina Stepinska and Lino Gon{\cc}alves and Vyacheslav Mareev and Zonara Vasilijevic and Igor Riecansky and Kenda, {Miran F.} and Annika Rosengren and Peter Buser and Tugrul Okay and Oleg Sychov and Peter Schofield and Anselm Gitt and G. Rosano and {EuroHeart Survey Investigators}",
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TY - JOUR

T1 - EuroHeart Failure Survey II (EHFS II)

T2 - A survey on hospitalized acute heart failure patients: Description of population

AU - Nieminen, Markku S.

AU - Brutsaert, Dirk

AU - Dickstein, Kenneth

AU - Drexler, Helmut

AU - Follath, Ferenc

AU - Harjola, Veli Pekka

AU - Hochadel, Matthias

AU - Komajda, Michel

AU - Lassus, Johan

AU - Lopez-Sendon, Jose Luis

AU - Ponikowski, Piotr

AU - Tavazzi, Luigi

AU - Manini, Malika

AU - Bramley, Claire

AU - Laforest, Valerie

AU - Taylor, Charles

AU - Hochadel, M.

AU - Huber, Kurt

AU - De Backer, Guy

AU - Sirakova, Vera

AU - Cerbak, Roman

AU - Thayssen, Per

AU - Abdel Aziz, Osama

AU - Tammam, Khalid

AU - Lehto, Seppo

AU - Delahaye, François

AU - Kobulia, Bondo

AU - Zeymer, Uwe

AU - Cokkinos, Dennis

AU - Krematisnos, Dimitrios

AU - Karlocai, Kristof

AU - Shelley, Emer

AU - Behar, Shlomo

AU - Maggioni, Aldo

AU - Grabauskiene, Virginija

AU - Deckers, Jaap

AU - Asmussen, Inger

AU - Stepinska, Janina

AU - Gonçalves, Lino

AU - Mareev, Vyacheslav

AU - Vasilijevic, Zonara

AU - Riecansky, Igor

AU - Kenda, Miran F.

AU - Rosengren, Annika

AU - Buser, Peter

AU - Okay, Tugrul

AU - Sychov, Oleg

AU - Schofield, Peter

AU - Gitt, Anselm

AU - Rosano, G.

AU - EuroHeart Survey Investigators

PY - 2006

Y1 - 2006

N2 - Aims The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics,aetiology, treatment, and outcome of acute heart failure (AHF) in Europe in relation to the guidelines on the diagnosis and treatment of AHF published by the European Society of Cardiology. Methods and results Patients hospitalized for AHF were recruited by 133 centres in 30 European countries. Three thousand five hundred and eighty patients were entered into the database by the end of August 2005. Mean age was 70 years, and 61% of patients were male. New-onset AHF (de novo AHF) was diagnosed in 37%, of which 42% was due to acute coronary syndromes (ACS). Clinical classification according to the guidelines divided AHF patients into (i) decompensated HF (65%), (ii) pulmonary oedema (16%), (iii) HF and hypertension (11%), (iv) cardiogenic shock (4%), and (v) right HF (3%). Coronary heart disease, hypertension, and atrial fibrillation were the most common underlying conditions. Arrhythmias, valvular dysfunction, and ACS were each present as precipitating factor in one-third of cases. Preserved left ventricular ejection fraction (≥45%) was observed in 34%. Valvular disorders were common, especially mitral regurgitation (MR) which was reported on echocardiography in 80% of patients. Median length of stay was 9 days, and in-hospital mortality 6.7%. At discharge, 80% of patients were on angiotensin-converting enzyme-inhibitors or angiotensin receptor blockers, whereas 61% were taking beta-blocker medication. Conclusion Decompensated HF is the most common clinical presentation of AHF patients. More than one-third of AHF patients do not have a previous history of HF, and new-onset HF is often caused by ACS. Preserved systolic function is found in a substantial proportion of the patients. The prevalence of valvular dysfunction is strikingly high and contributes to the clinical presentation. The EHFS II on AHF verified that the use of evidence-based HF medication was well adopted to clinical practice.

AB - Aims The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics,aetiology, treatment, and outcome of acute heart failure (AHF) in Europe in relation to the guidelines on the diagnosis and treatment of AHF published by the European Society of Cardiology. Methods and results Patients hospitalized for AHF were recruited by 133 centres in 30 European countries. Three thousand five hundred and eighty patients were entered into the database by the end of August 2005. Mean age was 70 years, and 61% of patients were male. New-onset AHF (de novo AHF) was diagnosed in 37%, of which 42% was due to acute coronary syndromes (ACS). Clinical classification according to the guidelines divided AHF patients into (i) decompensated HF (65%), (ii) pulmonary oedema (16%), (iii) HF and hypertension (11%), (iv) cardiogenic shock (4%), and (v) right HF (3%). Coronary heart disease, hypertension, and atrial fibrillation were the most common underlying conditions. Arrhythmias, valvular dysfunction, and ACS were each present as precipitating factor in one-third of cases. Preserved left ventricular ejection fraction (≥45%) was observed in 34%. Valvular disorders were common, especially mitral regurgitation (MR) which was reported on echocardiography in 80% of patients. Median length of stay was 9 days, and in-hospital mortality 6.7%. At discharge, 80% of patients were on angiotensin-converting enzyme-inhibitors or angiotensin receptor blockers, whereas 61% were taking beta-blocker medication. Conclusion Decompensated HF is the most common clinical presentation of AHF patients. More than one-third of AHF patients do not have a previous history of HF, and new-onset HF is often caused by ACS. Preserved systolic function is found in a substantial proportion of the patients. The prevalence of valvular dysfunction is strikingly high and contributes to the clinical presentation. The EHFS II on AHF verified that the use of evidence-based HF medication was well adopted to clinical practice.

KW - Acute heart failure

KW - Demographics

KW - Echocardiography

KW - EuroHeart Survey

KW - Treatment

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