European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager

Mohamed R. Daha

Reinhard Würzner, Francesco Tedesco, Peter Garred, Tom Eirik Mollnes, Lennart Truedsson, Malcolm W. Turner, Yngve Sommarin, Jörgen Wieslander, Robert B. Sim

Research output: Contribution to journalArticle

Abstract

A whole complement ELISA-based assay kit, primarily designed to screen for deficiencies in components of the complement system was developed during a European Union grant involving more than a dozen European scientists and a small-medium enterprise company (Wieslab, which later merged into Eurodiagnostica). The consortium was led by Prof. Mohamed R. Daha who had already guided a preceding European grant which prepared the ground for this endeavor to create a novel and sophisticated complement measurement tool. The final result of the grant was a scientific publication (Seelen et al., 2005, J. Immunol. Methods 296, 187-198) and a commercially available complement deficiency screening kit, WIESLAB® Complement system Screen. Thereafter, the group decided to carry on with a grant, located at Innsbruck Medical University, and supported by royalties and unrestricted educational grants from Eurodiagnostica, Malmö, entitled "Search for Applications for WIESLAB® Complement system Screen (SAW)" with the aim to look for further applications of this assay. During the latter project the group organized several scientific meetings aimed at evaluating the use of the assay as well as developing further branches of its platform. A look back over almost two decades reveals a great story of excellent research which was also commercially successful, fulfilling the aims of European Union grants. It is also a story of ageless friendship, only possible due to the vision and guidance of an exceptional manager: Moh Daha.

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalMolecular Immunology
Volume68
Issue number1
DOIs
Publication statusPublished - Nov 1 2015

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Organized Financing
European Union
Enzyme-Linked Immunosorbent Assay
Training Support
Publications
Research

Keywords

  • Complement
  • Daha
  • Deficiency
  • Diagnostics
  • ELISA
  • Screening

ASJC Scopus subject areas

  • Molecular Biology
  • Immunology

Cite this

European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager : Mohamed R. Daha. / Würzner, Reinhard; Tedesco, Francesco; Garred, Peter; Mollnes, Tom Eirik; Truedsson, Lennart; Turner, Malcolm W.; Sommarin, Yngve; Wieslander, Jörgen; Sim, Robert B.

In: Molecular Immunology, Vol. 68, No. 1, 01.11.2015, p. 63-66.

Research output: Contribution to journalArticle

Würzner, Reinhard ; Tedesco, Francesco ; Garred, Peter ; Mollnes, Tom Eirik ; Truedsson, Lennart ; Turner, Malcolm W. ; Sommarin, Yngve ; Wieslander, Jörgen ; Sim, Robert B. / European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager : Mohamed R. Daha. In: Molecular Immunology. 2015 ; Vol. 68, No. 1. pp. 63-66.
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