Evaluating breast cancer risk: Available models to assess individual breast cancer risk and probability to be a BRCA mutation carrier

B. Pasini, G. C Casalis Cavalchini, T. Genovese, S. Manoukian

Research output: Contribution to journalArticle

Abstract

Several models have been generated to estimate breast cancer risk and to predict the probability to identify a BRCA1 or BRCA2 germ line mutation. Each model, based on a slightly different study design and purpose, takes into account a definite number of relevant parameters and ultimately pertains to a specific cohort of women or population. Aim of this work is to underline validity and limits of available tools and their appropriate use in the daily practice.

Original languageEnglish
Pages (from-to)23-29
Number of pages7
JournalJournal of Experimental and Clinical Cancer Research
Volume21
Issue number3 SUPPL.
Publication statusPublished - Sep 2002

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Keywords

  • BRCA1 and BRCA2
  • Breast cancer
  • Penetrance
  • Risk factors
  • Risk models

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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