Evaluation by electron microscopy techniques of asbestos contamination in industrial, cosmetic, and pharmaceutical talcs

L. Paoletti, S. Caiazza, G. Donelli, F. Pocchiari

Research output: Contribution to journalArticle

Abstract

Talc powders from national and international markets were analyzed in order to assess their fiber contents and the proportion of asbestos in the fibrous material. Samples of talc powders used as excipients in pharmaceutical and cosmetic preparations demonstrated fiber contents up to 30% of total particles. About a half of the talc powders revealed the presence of asbestos: in five samples chrysotile (a serpentine asbestos) was present, in the other ones tremolite and anthophyllite (an amphibole asbestos). The amounts of asbestos vary up to 90% in the different samples of the fibrous fraction. About 75% of observed asbestos fibers were thinner than 0.4 μm, i.e., below the resolving power of light microscopy which until now was the most utilized technique for evaluating the environmental pollution due to asbestos.

Original languageEnglish
Pages (from-to)222-235
Number of pages14
JournalRegulatory Toxicology and Pharmacology
Volume4
Issue number3
DOIs
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Toxicology

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