Evaluation of a rapid bedside test for the quantitative determination of C-reactive protein

Susanna Esposito, Elena Tremolati, Enrica Begliatti, Samantha Bosis, Laura Gualtieri, Nicola Principi

Research output: Contribution to journalArticlepeer-review


Regardless of its origin, any condition associated with inflammation is accompanied by an increase in serum C-reactive protein levels. This study compared the results of a rapid test for the bedside assay of C-reactive protein (QuikRead CRP, Orion Corporation, Orion Diagnostica, Espoo, Finland) with those of a standard laboratory assay in samples taken from 231 children aged less than 14 years (126 males; median age 4.7 years) attending the Emergency Department of Milan University's Institute of Pediatrics because of acute respiratory infection. The two methods showed similar median C-reactive protein levels (standard laboratory assay: 34.7 mg/L, range 4-199 mg/L; QuikRead CRP: 33.3 mg/L, range 70 mg/L. This study shows for the first time that the rapid QuikRead CRP test can be performed at the bedside or in an outpatient clinic and, in less than 5 min, gives the same quantitative results as those obtained using a more complex routine laboratory method.

Original languageEnglish
Pages (from-to)438-440
Number of pages3
JournalClinical Chemistry and Laboratory Medicine
Issue number4
Publication statusPublished - Feb 7 2005


  • Acute phase response
  • C-reactive protein
  • Children
  • Markers of infection
  • Rapid tests

ASJC Scopus subject areas

  • Clinical Biochemistry


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