Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis

Carla Colombo, Aldo Roda, Enrico Roda, Lucia Piceni Sereni, Daniela Maspero, Anna Maria Giunta, Luigi Barbara

Research output: Contribution to journalArticle

Abstract

Serum levels of ursodeoxycholic acid (UDCA) were measured by radioimmunoassay in 20 children with cystic fibrosis (CF) and in eight controls, who had received 300 mg of this bile acid orally. Area under the curve (AUC) after UDCA load was significantly reduced (25.24±9.54) in CF patients, as compared to controls (52.98±5.87 mean values±sd percent dose/literxhrxkg body weight, P

Original languageEnglish
Pages (from-to)306-311
Number of pages6
JournalDigestive Diseases and Sciences
Volume28
Issue number4
DOIs
Publication statusPublished - Apr 1983

ASJC Scopus subject areas

  • Gastroenterology

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