Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis

Carla Colombo; Aldo Roda; Enrico Roda; Lucia Piceni Sereni; Daniela Maspero; Anna Maria Giunta; Luigi Barbara

doi:10.1007/BF01324946

Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis

Carla Colombo, Aldo Roda, Enrico Roda, Lucia Piceni Sereni, Daniela Maspero, Anna Maria Giunta, Luigi Barbara

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Serum levels of ursodeoxycholic acid (UDCA) were measured by radioimmunoassay in 20 children with cystic fibrosis (CF) and in eight controls, who had received 300 mg of this bile acid orally. Area under the curve (AUC) after UDCA load was significantly reduced (25.24±9.54) in CF patients, as compared to controls (52.98±5.87 mean values±sd percent dose/literxhrxkg body weight, P

Original language	English
Pages (from-to)	306-311
Number of pages	6
Journal	Digestive Diseases and Sciences
Volume	28
Issue number	4
DOIs	https://doi.org/10.1007/BF01324946
Publication status	Published - Apr 1983

ASJC Scopus subject areas

Gastroenterology

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10.1007/BF01324946

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title = "Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis",

abstract = "Serum levels of ursodeoxycholic acid (UDCA) were measured by radioimmunoassay in 20 children with cystic fibrosis (CF) and in eight controls, who had received 300 mg of this bile acid orally. Area under the curve (AUC) after UDCA load was significantly reduced (25.24±9.54) in CF patients, as compared to controls (52.98±5.87 mean values±sd percent dose/literxhrxkg body weight, P",

author = "Carla Colombo and Aldo Roda and Enrico Roda and Sereni, {Lucia Piceni} and Daniela Maspero and Giunta, {Anna Maria} and Luigi Barbara",

year = "1983",

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volume = "28",

pages = "306--311",

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AU - Colombo, Carla

AU - Roda, Aldo

AU - Roda, Enrico

AU - Sereni, Lucia Piceni

AU - Maspero, Daniela

AU - Giunta, Anna Maria

AU - Barbara, Luigi

PY - 1983/4

Y1 - 1983/4

N2 - Serum levels of ursodeoxycholic acid (UDCA) were measured by radioimmunoassay in 20 children with cystic fibrosis (CF) and in eight controls, who had received 300 mg of this bile acid orally. Area under the curve (AUC) after UDCA load was significantly reduced (25.24±9.54) in CF patients, as compared to controls (52.98±5.87 mean values±sd percent dose/literxhrxkg body weight, P

AB - Serum levels of ursodeoxycholic acid (UDCA) were measured by radioimmunoassay in 20 children with cystic fibrosis (CF) and in eight controls, who had received 300 mg of this bile acid orally. Area under the curve (AUC) after UDCA load was significantly reduced (25.24±9.54) in CF patients, as compared to controls (52.98±5.87 mean values±sd percent dose/literxhrxkg body weight, P

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Evaluation of an oral ursodeoxycholic acid load in the assessment of bile acid malabsorption in cystic fibrosis

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