TY - JOUR
T1 - Evaluation of cardiac autonomic modulation using symbolic dynamics after cardiac transplantation
AU - Moura-Tonello, Sílvia Cristina Garcia de
AU - Carvalho, Vitor Oliveira
AU - de Godoy, Moacir Fernandes
AU - Porta, Alberto
AU - Leal, Ângela Merice de Oliveira
AU - Bocchi, Edimar Alcides
AU - Catai, Aparecida Maria
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Objective: To characterize the behavior of cardiac autonomic modulation in individuals with different times after orthotopic heart transplantation (HTx) using symbolic dynamics analysis. Methods: Sixty patients were evaluated after HTx. We recorded their instantaneous R–R intervals (RRi) by cardiac monitor Polar® RS800CX™ (Polar Electro Oy, Kempele, Finland) for 10 minutes. The same sequence of RRi with 256 consecutive beats was used to perform spectral analysis and symbolic dynamics analysis. We used hierarchical clustering to form groups. One-way analysis of variance (ANOVA) (with Holm-Sidak method) or one-way Kruskal-Wallis test (with Dunn´s post-hoc test) was used to analyze the difference between groups. Linear correlation analysis between variables was performed using Pearson’s or Spearman’s tests. P-value < 0.05 was considered statistically significant. Results: The 0V% index increased, the 2UV% index and the normalized complexity index decreased with an increase of HTx postoperative time. There were a negative correlation between complexity indexes and 0V% and a positive correlation between complexity indexes and 2UV%. Conclusion: Symbolic dynamics indexes were able to show a specific cardiac autonomic modulation pattern for HTx recipients with different postoperative times.
AB - Objective: To characterize the behavior of cardiac autonomic modulation in individuals with different times after orthotopic heart transplantation (HTx) using symbolic dynamics analysis. Methods: Sixty patients were evaluated after HTx. We recorded their instantaneous R–R intervals (RRi) by cardiac monitor Polar® RS800CX™ (Polar Electro Oy, Kempele, Finland) for 10 minutes. The same sequence of RRi with 256 consecutive beats was used to perform spectral analysis and symbolic dynamics analysis. We used hierarchical clustering to form groups. One-way analysis of variance (ANOVA) (with Holm-Sidak method) or one-way Kruskal-Wallis test (with Dunn´s post-hoc test) was used to analyze the difference between groups. Linear correlation analysis between variables was performed using Pearson’s or Spearman’s tests. P-value < 0.05 was considered statistically significant. Results: The 0V% index increased, the 2UV% index and the normalized complexity index decreased with an increase of HTx postoperative time. There were a negative correlation between complexity indexes and 0V% and a positive correlation between complexity indexes and 2UV%. Conclusion: Symbolic dynamics indexes were able to show a specific cardiac autonomic modulation pattern for HTx recipients with different postoperative times.
KW - Autonomic Nervous System
KW - Heart Rate Variability
KW - Heart Transplantation
KW - Nonlinear Dynamics
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U2 - 10.21470/1678-9741-2019-0236
DO - 10.21470/1678-9741-2019-0236
M3 - Article
C2 - 31719008
AN - SCOPUS:85074773312
VL - 34
SP - 572
EP - 580
JO - Brazilian Journal of Cardiovascular Surgery
JF - Brazilian Journal of Cardiovascular Surgery
SN - 0102-7638
IS - 5
ER -