Valutazione della capacità funzionale cardiorespiratoria in bambini e giovani operati per tetralogia di Fallot.

Translated title of the contribution: Evaluation of cardiorespiratory function in children and adolescents with repaired tetralogy of Fallot

M. Dall'Olio, F. M. Picchio, S. Specchia, M. Bonvicini, B. Magnani

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

METHODS: To evaluate the cardiopulmonary exercise response of children and youngs operated upon for Tetralogy of Fallot (ToF) and to establish possible relationship with clinical and echocardiographic parameters we studied 24 pts, 14 males and 10 females, aged 14.5 +/- years; the age at repair was 5.2 +/- years and follow-up after correction was 8.6 +/- 3.2 years. All the pts were in NYHA functional class I; 8 pts had residual hemodynamic sequelae and 3 pts were on oral treatment. Cardiopulmonary exercise response with bicycle ergometer and incremental workload (25 watts/2 minutes), respiratory gas measurement with peak oxygen consumption (peak VO2) and ventilatory anaerobic threshold (VAT), were investigated in each patient. The data obtained were compared with those of control group of 103 healthy children and adolescents (59 males, 44 females, age 12.9 +/- 2.4 years) to the purpose of statistical analysis. RESULTS: The series of operated ToF pts showed 15-20% reduction in cardio-respiratory parameters, compared to healthy controls. a) Pts operated after the age of 5 years showed a significant reduction in peak VO2 compared to those operated at an earlier age (21 +/- 3.4 vs 35.4 +/- 7.5, p = 0.001) with; b) inverse correlation between peak VO2 and age at operation (r = -0.5, p = 0.01); c) 8 pts with residual hemodynamic sequelae (pulmonary regurgitation and/or ventricular outflow obstruction) showed the worse cardio-pulmonary capacity (peak VO2 27.5 +/- 7 vs 36.1 +/-8.1, p

Original languageItalian
Pages (from-to)1285-1294
Number of pages10
JournalGiornale Italiano di Cardiologia
Volume25
Issue number10
Publication statusPublished - Oct 1995

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Tetralogy of Fallot
Hemodynamics
Pulmonary Valve Insufficiency
Exercise
Anaerobic Threshold
Lung Volume Measurements
Ventricular Outflow Obstruction
Workload
Oxygen Consumption
Gases
Control Groups
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Valutazione della capacità funzionale cardiorespiratoria in bambini e giovani operati per tetralogia di Fallot. / Dall'Olio, M.; Picchio, F. M.; Specchia, S.; Bonvicini, M.; Magnani, B.

In: Giornale Italiano di Cardiologia, Vol. 25, No. 10, 10.1995, p. 1285-1294.

Research output: Contribution to journalArticle

Dall'Olio, M. ; Picchio, F. M. ; Specchia, S. ; Bonvicini, M. ; Magnani, B. / Valutazione della capacità funzionale cardiorespiratoria in bambini e giovani operati per tetralogia di Fallot. In: Giornale Italiano di Cardiologia. 1995 ; Vol. 25, No. 10. pp. 1285-1294.
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abstract = "METHODS: To evaluate the cardiopulmonary exercise response of children and youngs operated upon for Tetralogy of Fallot (ToF) and to establish possible relationship with clinical and echocardiographic parameters we studied 24 pts, 14 males and 10 females, aged 14.5 +/- years; the age at repair was 5.2 +/- years and follow-up after correction was 8.6 +/- 3.2 years. All the pts were in NYHA functional class I; 8 pts had residual hemodynamic sequelae and 3 pts were on oral treatment. Cardiopulmonary exercise response with bicycle ergometer and incremental workload (25 watts/2 minutes), respiratory gas measurement with peak oxygen consumption (peak VO2) and ventilatory anaerobic threshold (VAT), were investigated in each patient. The data obtained were compared with those of control group of 103 healthy children and adolescents (59 males, 44 females, age 12.9 +/- 2.4 years) to the purpose of statistical analysis. RESULTS: The series of operated ToF pts showed 15-20{\%} reduction in cardio-respiratory parameters, compared to healthy controls. a) Pts operated after the age of 5 years showed a significant reduction in peak VO2 compared to those operated at an earlier age (21 +/- 3.4 vs 35.4 +/- 7.5, p = 0.001) with; b) inverse correlation between peak VO2 and age at operation (r = -0.5, p = 0.01); c) 8 pts with residual hemodynamic sequelae (pulmonary regurgitation and/or ventricular outflow obstruction) showed the worse cardio-pulmonary capacity (peak VO2 27.5 +/- 7 vs 36.1 +/-8.1, p",
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