Evaluation of central opioid tonus in menstrual migraine.

F. Petraglia, E. Martignoni, D. Sola, C. Cicoli, F. Facchinetti, G. Nappi, A. R. Genazzani

Research output: Contribution to journalArticlepeer-review


The aim of this study is to make an evaluation of the activity of endogenous opioid tonus in patients affected by menstrual migraine. We tested the LH response to naloxone injection, an opiate receptor antagonist, in 18 migraineurs in the early and late luteal periods going towards the attacks. The lack of any response in the latter group demonstrates an opioid disregulation in this kind of pathology.

Original languageEnglish
Pages (from-to)98-100
Number of pages3
Volume3 Suppl 1
Publication statusPublished - Aug 1983

ASJC Scopus subject areas

  • Clinical Neurology


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