Evaluation of different adiposity indices and association with metabolic syndrome risk in obese children: Is there a winner?

Alessandro Leone, Sara Vizzuso, Paolo Brambilla, Chiara Mameli, Simone Ravella, Ramona De Amicis, Alberto Battezzati, Gianvincenzo Zuccotti, Simona Bertoli, Elvira Verduci

Research output: Contribution to journalArticlepeer-review


Body shape index (ABSI) and triponderal mass index (TMI) have been recently associated with cardiovascular risk in adults. A cross-sectional study was conducted to evaluate the relationship between different anthropometric adiposity indexes and metabolic syndrome (MetS) in Caucasian obese children and adolescents. Consecutive obese children aged ≥7 years have been enrolled. Anthropometric parameters, body composition (by bioelectrical impedance), and systolic and diastolic blood pressure have been measured. Fasting blood samples have been analyzed for lipids, insulin, glucose. A multivariate logistic regression analyses, with body mass index z-score, waist to height ratio, ABSI z-score, TMI, conicity index as predictors for MetS (IDEFICS and IDF criteria according to age) has been performed. Four hundred and three (179 boys and 224 girls) obese children, aged 7–20 years, have been evaluated. When we explored the joint contribution of each anthropometric and adiposity index of interest and BMIz on the risk of MetS, we found that the inclusion of ABSIz improved the prediction of MetS compared to BMIz alone. ABSI-BMI can be a useful index for evaluating the relative contribution of central obesity to cardiometabolic risk in clinical management of obese children and adolescents.

Original languageEnglish
Article number4083
JournalInternational Journal of Molecular Sciences
Issue number11
Publication statusPublished - Jun 1 2020


  • Adiposity indices
  • Childhood obesity
  • Metabolic syndrome

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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