Evaluation of evoked potentials and lymphocyte subsets as possible markers of multiple sclerosis

One year follow up of 30 patients

A. Ghezzi, M. Zaffaroni, D. Caputo, R. Montanini, C. L. Cazzullo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Evoked potentials and T-lymphocyte helper/suppressor ratio (H/S) were evaluated serially together with neurological status in 30 definite multiple sclerosis patients to evaluate their possible role in monitoring disease progression. Evoked potentials in many cases reflected the clinical status of the pathways tested, but some exceptions were observed, probably due to subclinical relapses or physical factors. In some instances the occurrence of subclinical relapses was suggested by increased H/S ratios. Serial H/S values increased in parallel with clinical and subclinical relapses, and seemed to show specific patterns in relation to the type of clinical course (relapsing, stable, chronic progressive). Our results suggest that evoked potentials and H/S ratio serial analysis can contribute to a better assessment of the progress of multiple sclerosis.

Original languageEnglish
Pages (from-to)913-919
Number of pages7
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume49
Issue number8
DOIs
Publication statusPublished - 1986

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Lymphocyte Subsets
Evoked Potentials
Multiple Sclerosis
Recurrence
Critical Pathways
Helper-Inducer T-Lymphocytes
Disease Progression

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health

Cite this

Evaluation of evoked potentials and lymphocyte subsets as possible markers of multiple sclerosis : One year follow up of 30 patients. / Ghezzi, A.; Zaffaroni, M.; Caputo, D.; Montanini, R.; Cazzullo, C. L.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 49, No. 8, 1986, p. 913-919.

Research output: Contribution to journalArticle

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