Evaluation of gait in Duchenne Muscular Dystrophy: Relation of 3D gait analysis to clinical assessment

Research output: Contribution to journalArticlepeer-review


Walking ability in Duchenne Muscular Dystrophy (DMD) deteriorates progressively until complete loss of the function. Interventions aimed at maintaining ambulatory ability relies on accurate clinical-based scores and evaluations of walking. This kind of assessment has intrinsic limitations. A 3D optoelectronic system could provide elements useful for the functional evaluation of patients with DMD. Nineteen boys with DMD were evaluated using the 6-Minutes Walking Test, North Star Ambulatory Assessment and 3D gait analysis. Participants' gait parameters were compared to those of an age-matched control group and correlated with standard clinical scores. Seventeen kinematic variables differed between DMD and control groups. Strong correlations with North Star Ambulatory Assessment were found for stride width, gait velocity and ankle angles on the sagittal plane. The 6-Minutes Walking test did not correlate with investigated kinematic variables but showed a correlation with North Star Ambulatory Assessment. Our data support the reported DMD gait pattern characterized by increased anterior pelvic tilt and ankle plantar flexion. The stride width and ankle kinematics emerged as the main representative gait parameters of DMD global ambulatory status. Although preliminary, our findings suggest that 3D gait analysis may provide useful objective and accurate parameters reflecting the functional ability of individuals with DMD.

Original languageEnglish
Pages (from-to)920-929
Number of pages10
JournalNeuromuscular Disorders
Issue number12
Publication statusPublished - Dec 2019


Dive into the research topics of 'Evaluation of gait in Duchenne Muscular Dystrophy: Relation of 3D gait analysis to clinical assessment'. Together they form a unique fingerprint.

Cite this