Evaluation of hypercapnia in Obstructive Sleep Apnea (OSA)

Onofrio Resta, P. Guido, M. P. Foschino, V. Picca, F. Affuso, M. Sergi, M. Rizzi

Research output: Contribution to journalArticlepeer-review


Purpose: The reasons for hypercapnia in OSA patients are not completely known. Some authors suggest that the obstructive airway defect is a major factor to hypercapnia. In the present study we determined the relationship between chronic hypercapnia and anthropometric data, pulmonary functional tests and nocturnal polysomnographic findings, in 131 consecutively unselected OSA patients from two sleep Centers. Methods: The patients were 101 males, 30 females with mean age 53.2 years, mean BMI 36,4 kg/m2, mean FEV1 81,2% predicted, mean FVC 83,9% predicted, mean Minimal nocturnal saturation, Nadir 67%, mean AHI 47,4/hour, without acute respiratory and cardiac failure. The OSA patients with hypercapnia (PaCO2 >45 mmHg) were 27 (20,6%), with COPD (FEV1/FVC

Original languageEnglish
Issue number4 SUPPL.
Publication statusPublished - Oct 1996

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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