Evaluation of morbidity of multi-channel pressure-flow studies

Daniele Porru, Giuliana Madeddu, Giuliana Campus, Ignazio Montisci, Roberto Mario Scarpa, Enzo Usai

Research output: Contribution to journalArticlepeer-review


This prospective study was carried out to evaluate the morbidity and complication rate of invasive urodynamics of the lower urinary tract after receiving oral antibiotic prophylactic treatment. A total of 105 patients, 55 men and 50 women, were included in the study and underwent pressure flow study (PFS) as part of the diagnostic assessment. Clinical diagnosis was prostatic obstruction from benign prostatic hyperplasia (BPH) in men and stress urinary incontinence or voiding dysfunction in women. Urine was screened for infection both before and after testing, and the incidence of urinary tract infections (UTI), dysuria, and other complications were assessed at 1-week follow-up to evaluate post-investigation morbidity. Dysuria of mild degree was experienced by 33% of patients, with no significant difference between male and female patients. Post-investigational UTI and fever were reported in 3.6% of men and 4% of women. Six patients had macroscopic hematuria of mild degree. No patient had urinary retention or severe complaints after the investigation and no patient required hospitalization. Post-void residual volume was higher in men with BPH obstruction compared to women; a significant difference between post- investigational UTI and residual volume could not be demonstrated (P = 0.8). We conclude that the objective morbidity rate of invasive urodynamic investigation is low. Mild dysuria is common, while severe complications, fever, and hematuria are seldom reported, and the risk of developing UTIs is low with antibiotic prophylaxis, with no significant difference between men and women.

Original languageEnglish
Pages (from-to)647-652
Number of pages6
JournalNeurourology and Urodynamics
Issue number6
Publication statusPublished - 1999


  • Micturition complaints
  • Urinary tract infection
  • Urodynamics

ASJC Scopus subject areas

  • Nephrology
  • Clinical Neurology
  • Urology


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