Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus

Stefania Cartella, Ilaria Cavazzana, Angela Ceribelli, Flora Inverardi, Angela Tincani, Franco Franceschini

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: We retrospectively compared disease activity, treatment, clinical and laboratory features, and rate of mortality of 535 SLE patients with adult and late disease onset. Methods: patients were divided into two groups based on the onset of the disease before or after 50 years of age. Clinical data were collected from medical reports. Disease activity was measured by ECLAM score. Parameters were compared by χ2-test, Fisher's test, Student's t or the Mann-Whitney test. Results: Forty patients (7.5%) were included in the late SLE onset group (group A), while 495 (92.5%) in the adult SLE onset group (group B). Sicca symptoms were more frequent in group A (p

Original languageEnglish
Pages (from-to)363-368
Number of pages6
JournalAutoimmunity
Volume46
Issue number6
DOIs
Publication statusPublished - Sep 2013

Keywords

  • Age
  • Autoimmunity
  • ECLAM
  • Sicca
  • Treatment condition

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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