Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus

Stefania Cartella; Ilaria Cavazzana; Angela Ceribelli; Flora Inverardi; Angela Tincani; Franco Franceschini

doi:10.3109/08916934.2013.794793

Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus

Stefania Cartella, Ilaria Cavazzana, Angela Ceribelli, Flora Inverardi, Angela Tincani, Franco Franceschini

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: We retrospectively compared disease activity, treatment, clinical and laboratory features, and rate of mortality of 535 SLE patients with adult and late disease onset. Methods: patients were divided into two groups based on the onset of the disease before or after 50 years of age. Clinical data were collected from medical reports. Disease activity was measured by ECLAM score. Parameters were compared by χ²-test, Fisher's test, Student's t or the Mann-Whitney test. Results: Forty patients (7.5%) were included in the late SLE onset group (group A), while 495 (92.5%) in the adult SLE onset group (group B). Sicca symptoms were more frequent in group A (p

Original language	English
Pages (from-to)	363-368
Number of pages	6
Journal	Autoimmunity
Volume	46
Issue number	6
DOIs	https://doi.org/10.3109/08916934.2013.794793
Publication status	Published - Sep 2013

Keywords

Age
Autoimmunity
ECLAM
Sicca
Treatment condition

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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Evaluation of mortality, disease activity, treatment, clinical and immunological features of adult and late onset systemic Lupus erythematosus. / Cartella, Stefania; Cavazzana, Ilaria; Ceribelli, Angela; Inverardi, Flora; Tincani, Angela; Franceschini, Franco.

In: Autoimmunity, Vol. 46, No. 6, 09.2013, p. 363-368.

Research output: Contribution to journal › Article › peer-review

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