Evaluation of myocardial perfusion and function by Technetium-99m methoxy isobutyl isonitrile before and after percutaneous transluminal coronary angioplasty preliminary results

L. Pace, S. Betocchi, F. Piscione, M. L M D Stefano, M. Chiariello, M. Salvatore.

Research output: Contribution to journalArticle

Abstract

Myocardial perfusion and function were evaluated with Tc-99m MIBI myocardial scintigraphy before and after percutaneous angioplasty in six patients. In addition to conventional stress-rest images (3 projections: 45° left anterior oblique, anterior, and left lateral), gated images were obtained at rest and during stress before and after angioplasty. Improvement in myocardial perfusion after angioplasty was demonstrated in all patients. The increase from rest to stress of radionuclide fractional shortening (an index of global left ventricular function computed on gated images) was greater after angioplasty than before (9% ± 7% versus - 0.5% ± 8%, respectively, p <0.05). Systolic wall thickening (an index of regional left ventricular function) showed a significantly greater rest-to-stress increase after angioplasty than before it in the regions supplied by treated vessels. Thus, Tc-99m MIBI myocardial scintigraphy is capable of evaluating myocardial perfusion and function.

Original languageEnglish
Pages (from-to)286-290
Number of pages5
JournalClinical Nuclear Medicine
Volume18
Issue number4
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Evaluation of myocardial perfusion and function by Technetium-99m methoxy isobutyl isonitrile before and after percutaneous transluminal coronary angioplasty preliminary results'. Together they form a unique fingerprint.

  • Cite this