74 preterm infants (range 27-35 wks), weighing less than 2000 g at birth (range 825-1990 g), on mechanical ventilation and/or exclusive parenteral nutrition for less than 15 days, were perspectively studied in order to evaluate their nutritional status and derive laboratory reference standards in relation to age, weight and type of milk. At a post-natal age of 15-60 days, a total of 110 balance studies were performed by collecting a 12-hour urine and a blood sample for the determination of pH, emoglobin, glucose, bilirubin, transaminases, alkaline phosphatase, total proteins, albumin and prealbumin in serum; creatinine, nitrogen urea, Ca, P, Mg in both serum and urine and C-peptide in urine, infants were divided in 3 groups: one fed fresh mothers' milk fortified with proteins, Ca, P, Mg and Na (MM, 35 balances), one fed a preterm formula (F, 34 balances) and one receiving both milks (41 balances). At the balance study, age, milk and protein intake, growth indices and most laboratory tests were not different among the 3 groups (T test and Mann-Whitney U test, p <0.01). Anyway serum Mg and urinary Mg, creatinine and C-peptide were significantly lower in the MM group. On the pooled data, hemoglobin (r -0.67), serum total bilirubin (r -0.57), creatinine (r -0.45) andALP (r 0.36) were significantly correlated with postnatal age, while creatininemia alone correlated with corrected age (r -0.36) and prealbumin with body weight (r 0.44). Since a number of blood and especially of urine values showed a non-normal distribution, we calculated their centiles, with are particularly useful in the clinical setting.
|Translated title of the contribution||Evaluation of nutritional status in preterm infants: Influence of age and maternal, formula, or mixed feeding|
|Number of pages||10|
|Journal||Rivista Italiana di Pediatria|
|Publication status||Published - Feb 1997|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health