Evaluation of pain, swelling and trismus after extraction of impacted third molars relative to the use of betamethasone in submucusal infiltration

D. Bertossi, D. Donadello, G. Ricciardi, U. Luciano, F. Zotti, R. Nocini, N. Kumar, A. Lucchese, U. Tacchino, M. Matarese, G. Manzini, D. De Santis, M. Albanese

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to evaluate the anti-inflammatory effect of a single 4 mg injection of submucosal betamethasone after extraction of impacted third molars. Single-centre, single-blinded, parallel group study; Forty-three patients were submitted to impacted third molar extraction. In this study, 4 mg single-dose submucosal betamethasone was injected in the interventional group, while in the control group nothing was injected. Postoperative measurement included pain via the VAS scale, swelling and trismus with facial measurements and maximum mouth openings, and finally nerve sensitivity. There was a significant difference between the two groups regarding trismic pain and edema. The use of a single 4 mg submucosal betamethasone injection leads to a reduction of oedema, trismus and pain in patients undergoing impacted third molar extraction. .

Original languageEnglish
Pages (from-to)9-17
Number of pages9
JournalJournal of Biological Regulators and Homeostatic Agents
Volume33
Issue numberinteger
Publication statusPublished - Jan 1 2019

Keywords

  • betamethasone
  • corticosteroids
  • third molar extraction

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Physiology
  • Immunology
  • Oncology
  • Endocrinology
  • Physiology (medical)
  • Cancer Research

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