Evaluation of patients' satisfaction of cervical ripening using dinoprostone by either intravaginal gel or pessary an open-label, randomized, prospective study

Antonella Ferraiolo, Ilaria Dellacasa, Giorgio Bentivoglio, Simone Ferrero, Nicola Ragni

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: To evaluate patient satisfaction of cervical ripening using dinoprostone (PGE 2) by either intravaginal gel or pessary. STUDY DESIGN: A group of 173 lliparous women requiring cervical ripening were recruited in the study and randomized to receive either intravaginal gel (Prepidil, Upjohn, Milan, Italy [group A]) or intravaginal pessary (Propess, Ferring Pharmaceuticals, Malmö, Sweden [group B]). Before administration of PGE 2 and after delivery, the patients answered a questionnaire investigating the anxiety and discomfort caused by cervical ripening. RESULTS: Of the group, 22 women did not adequately complete the questionnaire; therefore 151 women were included in the study. Before cervical ripening, anxiety and discomfort did not significantly differ between the two study groups; more patients in group A than in group B declared they would have preferred the other form of application. The intensity of pain experienced during the application of PGE 2 was higher in group B than in group A. For the future opportunity to choose the application necessary for cervical ripening, more patients in group B than in group A would change the form of application. CONCLUSION: Patient satisfaction with the two forms of treatment appears to be equally good. The application of the intravaginal pessary causes more discomfort than the vaginal gel.

Original languageEnglish
Pages (from-to)423-429
Number of pages7
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume55
Issue number10
Publication statusPublished - Oct 2010

Keywords

  • Cervical ripening
  • Dinoprostone
  • Labor induction
  • Patient satisfaction

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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