STH circadian secretion has been investigated in 11 acromegalic patients. The physiological STH nocturnal surge is not present in acromegaly, but when data are evaluated by Fourier's cosinus analysis, a rhythmicity is, however, found also in acromegaly. The characteristics of harmonics, namely periodicity, amplitudes and phases, are largely different in respect to pattern of normal subjects, where the rhythmicity is represented by an harmonics with 24-hour periodicity.
|Translated title of the contribution||Evaluation of pituitary functional periodicity by harmonic analysis. I). Circadian somatotropin secretion in acromegaly|
|Number of pages||7|
|Journal||Bollettino della Societa Italiana di Biologia Sperimentale|
|Publication status||Published - 1982|
ASJC Scopus subject areas