Evaluation of rapid assay for detection of Streptococcus pneumoniae urinary antigen among infants and young children with possible invasive pneumococcal disease

Susanna Esposito, Samantha Bosis, Rosaria Colombo, Patrizia Carlucci, Nadia Faelli, Emilio Fossali, Nicola Principi

Research output: Contribution to journalArticlepeer-review

Abstract

The usefulness of the rapid assay for detection of Streptococcus pneumoniae urinary antigen was evaluated in 155 children ages 1 to 60 months with suspected invasive pneumococcal disease and 200 healthy controls. Although the assay was highly sensitive in the children with invasive pneumococcal disease, it should be interpreted with caution in young patients because a positive urine test result may simply be the result of nasopharyngeal colonization.

Original languageEnglish
Pages (from-to)365-367
Number of pages3
JournalPediatric Infectious Disease Journal
Volume23
Issue number4
DOIs
Publication statusPublished - Apr 2004

Keywords

  • Binax NOW
  • Children
  • Invasive pneumococcal disease
  • Rapid antigen assay
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pediatrics, Perinatology, and Child Health

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