Evaluation of skeletal status by quantitative ultrasonometry in postmenopausal women without known risk factors for osteoporosis

Vincenzo Dario Mandato, Annalidia Sammartino, Costantino Di Carlo, Giovanni A. Tommaselli, Libuse Tauchmanovà, Antonio D'Elia, Carmine Nappi

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of our study was to evaluate bone density in Italian postmenopausal women without clinical risk factors for osteoporosis resident in the Naples area using quantitative ultrasonometry of bone (QUS). Subjects were 1149 Italian postmenopausal women (age: 54.9 ± 5.0 years (mean ± standard deviation); range: 45-74 years) resident in the Naples area. Clinical risk factors for osteoporosis resulting in exclusion from the study were family history of osteoporosis, dietary, smoking and alcohol habits, personal history of fractures and/or metabolic diseases. The following QUS parameters were calculated: amplitude-dependent speed of sound (AD-SoS), T-score and Z-score. We found significant inverse correlations between AD-SoS and age (r=-0.23), time since menopause (r=-0.25) and body mass index (BMI) (r=-0.16). The same was observed for T-score. In contrast, Z-score showed a significant positive correlation with age and time since menopause, and a negative correlation with BMI. A T-score suggestive of high risk for osteoporosis (less than -3.2) was found in 1.6% of subjects, while a T-score suggestive of moderate risk for osteoporosis (between -3.2 and -2) was found in 19.3% of patients. In this group of women without clinical risk factors for osteoporosis we found a very low prevalence of QUS results suggesting a high risk for osteoporosis. However, a condition of 'moderate' risk for osteoporosis was present in a remarkable percentage of these women.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalGynecological Endocrinology
Volume21
Issue number3
DOIs
Publication statusPublished - Sep 2005

Keywords

  • Menopause
  • Osteoporosis
  • Quantitative ultrasonometry of bone
  • Risk factors

ASJC Scopus subject areas

  • Endocrinology
  • Obstetrics and Gynaecology

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