Evaluation of the BDProbeTec ET system for direct detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary samples: A multicenter study

Gianna Mazzarelli, Laura Rindi, Paola Piccoli, Claudio Scarparo, Carlo Garzelli, Enrico Tortoli

Research output: Contribution to journalArticle

Abstract

We evaluated the BDProbeTec ET system (Becton Dickinson, Sparks, Md.), a strand displacement amplification-based technique, for direct detection of Mycobacterium tuberculosis in 867 clinical samples. Of 294 extrapulmonary specimens, 52 had positive results by both BDProbeTec ET and culture and 209 had negative results by both methods; sensitivity and specificity were 76.5 and 95.9%, respectively. After resolution of discrepancies, the sensitivity rose to 77.8%.

Original languageEnglish
Pages (from-to)1779-1782
Number of pages4
JournalJournal of Clinical Microbiology
Volume41
Issue number4
DOIs
Publication statusPublished - Apr 1 2003

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Mycobacterium tuberculosis
Multicenter Studies
Sensitivity and Specificity
Lung

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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Evaluation of the BDProbeTec ET system for direct detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary samples : A multicenter study. / Mazzarelli, Gianna; Rindi, Laura; Piccoli, Paola; Scarparo, Claudio; Garzelli, Carlo; Tortoli, Enrico.

In: Journal of Clinical Microbiology, Vol. 41, No. 4, 01.04.2003, p. 1779-1782.

Research output: Contribution to journalArticle

Mazzarelli, Gianna ; Rindi, Laura ; Piccoli, Paola ; Scarparo, Claudio ; Garzelli, Carlo ; Tortoli, Enrico. / Evaluation of the BDProbeTec ET system for direct detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary samples : A multicenter study. In: Journal of Clinical Microbiology. 2003 ; Vol. 41, No. 4. pp. 1779-1782.
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