Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules

C. Bertulessi, P. Pigatto, A. Bigardi, P. Bosco, M. J. Lechuga, E. Colli, M. Scatigna

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An open clinical trial was performed on 24 healthy volunteers in order to evaluate the irritation potential of fenticonazole gynecologic ovules (200 and 600 mg). The contact-sensitizing potential of the two fenticonazole preparations was also investigated. There was no evidence of irritation after treatment with fenticonazole 200-mg or 600-mg ovules. The contact-sensitizing test was performed with fenticonazole 200-mg and 600-mg ovules and their respective excipients. Two subjects (one in the fenticonazole 200-mg group and one in the fenticonazole 600-mg excipients) showed signs of mild sensitization.

Original languageEnglish
Pages (from-to)1004-1008
Number of pages5
JournalCurrent Therapeutic Research
Volume47
Issue number6
Publication statusPublished - 1990

Fingerprint

Ovule
Excipients
fenticonazole
Healthy Volunteers
Clinical Trials

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bertulessi, C., Pigatto, P., Bigardi, A., Bosco, P., Lechuga, M. J., Colli, E., & Scatigna, M. (1990). Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules. Current Therapeutic Research, 47(6), 1004-1008.

Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules. / Bertulessi, C.; Pigatto, P.; Bigardi, A.; Bosco, P.; Lechuga, M. J.; Colli, E.; Scatigna, M.

In: Current Therapeutic Research, Vol. 47, No. 6, 1990, p. 1004-1008.

Research output: Contribution to journalArticle

Bertulessi, C, Pigatto, P, Bigardi, A, Bosco, P, Lechuga, MJ, Colli, E & Scatigna, M 1990, 'Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules', Current Therapeutic Research, vol. 47, no. 6, pp. 1004-1008.
Bertulessi, C. ; Pigatto, P. ; Bigardi, A. ; Bosco, P. ; Lechuga, M. J. ; Colli, E. ; Scatigna, M. / Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules. In: Current Therapeutic Research. 1990 ; Vol. 47, No. 6. pp. 1004-1008.
@article{3321ee94f2494ccea428f63cc3b2e74b,
title = "Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules",
abstract = "An open clinical trial was performed on 24 healthy volunteers in order to evaluate the irritation potential of fenticonazole gynecologic ovules (200 and 600 mg). The contact-sensitizing potential of the two fenticonazole preparations was also investigated. There was no evidence of irritation after treatment with fenticonazole 200-mg or 600-mg ovules. The contact-sensitizing test was performed with fenticonazole 200-mg and 600-mg ovules and their respective excipients. Two subjects (one in the fenticonazole 200-mg group and one in the fenticonazole 600-mg excipients) showed signs of mild sensitization.",
author = "C. Bertulessi and P. Pigatto and A. Bigardi and P. Bosco and Lechuga, {M. J.} and E. Colli and M. Scatigna",
year = "1990",
language = "English",
volume = "47",
pages = "1004--1008",
journal = "Current Therapeutic Research - Clinical and Experimental",
issn = "0011-393X",
publisher = "Excerpta Medica",
number = "6",

}

TY - JOUR

T1 - Evaluation of the contact-sensitizing and irritation potential of fenticonazole vaginal ovules

AU - Bertulessi, C.

AU - Pigatto, P.

AU - Bigardi, A.

AU - Bosco, P.

AU - Lechuga, M. J.

AU - Colli, E.

AU - Scatigna, M.

PY - 1990

Y1 - 1990

N2 - An open clinical trial was performed on 24 healthy volunteers in order to evaluate the irritation potential of fenticonazole gynecologic ovules (200 and 600 mg). The contact-sensitizing potential of the two fenticonazole preparations was also investigated. There was no evidence of irritation after treatment with fenticonazole 200-mg or 600-mg ovules. The contact-sensitizing test was performed with fenticonazole 200-mg and 600-mg ovules and their respective excipients. Two subjects (one in the fenticonazole 200-mg group and one in the fenticonazole 600-mg excipients) showed signs of mild sensitization.

AB - An open clinical trial was performed on 24 healthy volunteers in order to evaluate the irritation potential of fenticonazole gynecologic ovules (200 and 600 mg). The contact-sensitizing potential of the two fenticonazole preparations was also investigated. There was no evidence of irritation after treatment with fenticonazole 200-mg or 600-mg ovules. The contact-sensitizing test was performed with fenticonazole 200-mg and 600-mg ovules and their respective excipients. Two subjects (one in the fenticonazole 200-mg group and one in the fenticonazole 600-mg excipients) showed signs of mild sensitization.

UR - http://www.scopus.com/inward/record.url?scp=0025296901&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025296901&partnerID=8YFLogxK

M3 - Article

VL - 47

SP - 1004

EP - 1008

JO - Current Therapeutic Research - Clinical and Experimental

JF - Current Therapeutic Research - Clinical and Experimental

SN - 0011-393X

IS - 6

ER -