Abstract
We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.
| Original language | Italian |
|---|---|
| Pages (from-to) | 397-403 |
| Number of pages | 7 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 60 |
| Issue number | 2 |
| Publication status | Published - Feb 28 1984 |
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Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche. / Ghizzi, A.; Carlo Stella, C.; Bossi, M. T.; Gorini, M.
In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 60, No. 2, 28.02.1984, p. 397-403.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche.
AU - Ghizzi, A.
AU - Carlo Stella, C.
AU - Bossi, M. T.
AU - Gorini, M.
PY - 1984/2/28
Y1 - 1984/2/28
N2 - We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.
AB - We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021772177&partnerID=8YFLogxK
M3 - Articolo
C2 - 6712801
AN - SCOPUS:0021772177
VL - 60
SP - 397
EP - 403
JO - Bollettino della Societa Italiana di Biologia Sperimentale
JF - Bollettino della Societa Italiana di Biologia Sperimentale
SN - 0037-8771
IS - 2
ER -