Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche.

Translated title of the contribution: Evaluation of the distribution spectrum of bone marrow granulocyte-CFU and its prognostic significance in dysmyelopoietic syndromes

A. Ghizzi, C. Carlo Stella, M. T. Bossi, M. Gorini

Research output: Contribution to journalArticle

Abstract

We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.

Original languageItalian
Pages (from-to)397-403
Number of pages7
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume60
Issue number2
Publication statusPublished - Feb 28 1984

Fingerprint

Granulocyte-Macrophage Progenitor Cells
Myelodysplastic Syndromes
Granulocytes
Bone Marrow
Growth
Acute Myeloid Leukemia
Survival
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche. / Ghizzi, A.; Carlo Stella, C.; Bossi, M. T.; Gorini, M.

In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 60, No. 2, 28.02.1984, p. 397-403.

Research output: Contribution to journalArticle

@article{609b9d0d3f664d56a2504c92fafbed22,
title = "Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche.",
abstract = "We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their {"}in vitro{"} appearance time, transformation from cluster to colony, {"}in vitro{"} survival time and {"}in vitro{"} degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.",
author = "A. Ghizzi and {Carlo Stella}, C. and Bossi, {M. T.} and M. Gorini",
year = "1984",
month = "2",
day = "28",
language = "Italian",
volume = "60",
pages = "397--403",
journal = "Bollettino della Societa Italiana di Biologia Sperimentale",
issn = "0037-8771",
publisher = "Casa Editrice Idelson Gnocchi",
number = "2",

}

TY - JOUR

T1 - Valutazione dello spettro di distribuzione delle CFU-GM midollari e suo significato prognostico nelle sindromi dismielopoietiche.

AU - Ghizzi, A.

AU - Carlo Stella, C.

AU - Bossi, M. T.

AU - Gorini, M.

PY - 1984/2/28

Y1 - 1984/2/28

N2 - We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.

AB - We have studied bone marrow CFU-GM growth behaviour in 13 patients with Dysmyelopoietic Syndrome by means of the analytical scoring at two sequential times of aggregates. In this way we have distinguished aggregates according to their size, in clusters or colonies and grouped them according to their "in vitro" appearance time, transformation from cluster to colony, "in vitro" survival time and "in vitro" degeneration time. This statement of the study allow us to map CFU-GM subtypes in a percentage distribution related to the total growth of CFU-GM. Comparisons between absolute number of growth of different CFU-GM subtypes in DS vs Normal subjects show both significant and not significant differences, while comparisons between percentages of growth in DS vs Normal subjects did not show significant differences. With this work we suggest an outline for the study and the interpretation of CFU-GM growth patterns in the haematological disorders at risk of evolution in acute nonlymphocytic leukemia.

UR - http://www.scopus.com/inward/record.url?scp=0021772177&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021772177&partnerID=8YFLogxK

M3 - Articolo

C2 - 6712801

AN - SCOPUS:0021772177

VL - 60

SP - 397

EP - 403

JO - Bollettino della Societa Italiana di Biologia Sperimentale

JF - Bollettino della Societa Italiana di Biologia Sperimentale

SN - 0037-8771

IS - 2

ER -