Abstract
The present study was carried out on nine men, aged between 36 and 57 years (mean age, 45.3 ± 6.6 years), affected by mild essential arterial hypertension at World Health Organization stage I. All patients had been treated with beta-blockers for a period of one to six months. In all patients beta-blockers had normalized arterial blood pressure (ABP) values (systolic ABP, 141.6 ± 9.7 mmHg; diastolic ABP, 88.3 ± 3.5 mmHg), however, causing sexual impotence. Due to this side effect, beta-blockers were replaced with captopril (50 mg once daily) for two weeks. After this period, two subjects required 100 mg daily of captopril to achieve normal ABP, while the other two required a diuretic in addition to captopril 100 mg daily for normalization of their ABP. In six of the nine patients sexual impotence disappeared within two to four weeks of the change in therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 837-841 |
| Number of pages | 5 |
| Journal | Current Therapeutic Research |
| Volume | 46 |
| Issue number | 5 |
| Publication status | Published - 1989 |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
Evaluation of the effectiveness and tolerability of captopril in the treatment of essential arterial hypertension in nine subjects with sexual impotence secondary to the use of beta-blockers. / Antonicelli, R.; Piani, M.; Paciaroni, E.
In: Current Therapeutic Research, Vol. 46, No. 5, 1989, p. 837-841.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of the effectiveness and tolerability of captopril in the treatment of essential arterial hypertension in nine subjects with sexual impotence secondary to the use of beta-blockers
AU - Antonicelli, R.
AU - Piani, M.
AU - Paciaroni, E.
PY - 1989
Y1 - 1989
N2 - The present study was carried out on nine men, aged between 36 and 57 years (mean age, 45.3 ± 6.6 years), affected by mild essential arterial hypertension at World Health Organization stage I. All patients had been treated with beta-blockers for a period of one to six months. In all patients beta-blockers had normalized arterial blood pressure (ABP) values (systolic ABP, 141.6 ± 9.7 mmHg; diastolic ABP, 88.3 ± 3.5 mmHg), however, causing sexual impotence. Due to this side effect, beta-blockers were replaced with captopril (50 mg once daily) for two weeks. After this period, two subjects required 100 mg daily of captopril to achieve normal ABP, while the other two required a diuretic in addition to captopril 100 mg daily for normalization of their ABP. In six of the nine patients sexual impotence disappeared within two to four weeks of the change in therapy.
AB - The present study was carried out on nine men, aged between 36 and 57 years (mean age, 45.3 ± 6.6 years), affected by mild essential arterial hypertension at World Health Organization stage I. All patients had been treated with beta-blockers for a period of one to six months. In all patients beta-blockers had normalized arterial blood pressure (ABP) values (systolic ABP, 141.6 ± 9.7 mmHg; diastolic ABP, 88.3 ± 3.5 mmHg), however, causing sexual impotence. Due to this side effect, beta-blockers were replaced with captopril (50 mg once daily) for two weeks. After this period, two subjects required 100 mg daily of captopril to achieve normal ABP, while the other two required a diuretic in addition to captopril 100 mg daily for normalization of their ABP. In six of the nine patients sexual impotence disappeared within two to four weeks of the change in therapy.
UR - http://www.scopus.com/inward/record.url?scp=0024394262&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024394262&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024394262
VL - 46
SP - 837
EP - 841
JO - Current Therapeutic Research - Clinical and Experimental
JF - Current Therapeutic Research - Clinical and Experimental
SN - 0011-393X
IS - 5
ER -