Abstract
The efficiency of some components of the host defense system has been evaluated in 32 atopic patients with rhinitis, asthma or asthma and rhinitis. No alterations in components of complement (C3 and C4), serum immunoglobulins (IgG, IgA, and IgM) and neutrophil functional parameters were found. As expected, serum IgE values were higher than in controls. A decreased percentage of total circulating T lymphocytes, an increased percentage of Ia1-positive cells, but normal values of OKT4- and OKT8-positive T lymphocytes were demonstrated. However, a greater heterogeneity in the distribution of the suppressor-cytotoxic subset was shown in atopic patients.
| Original language | English |
|---|---|
| Pages (from-to) | 83-91 |
| Number of pages | 9 |
| Journal | Respiration |
| Volume | 50 |
| DOIs | |
| Publication status | Published - 1986 |
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Keywords
- Host defense system
- Polymorphonuclear neutrophil function tests
- T-lymphocyte subsets
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Physiology
Cite this
Evaluation of the host defense system in asthmatic patients. / Grassi, Giuliana Gialdroni; Zanon, Pietro; Fietta, Anna; Rose, Virginia De; Mangiarotti, Patrizia; Grassi, Carlo.
In: Respiration, Vol. 50, 1986, p. 83-91.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of the host defense system in asthmatic patients
AU - Grassi, Giuliana Gialdroni
AU - Zanon, Pietro
AU - Fietta, Anna
AU - Rose, Virginia De
AU - Mangiarotti, Patrizia
AU - Grassi, Carlo
PY - 1986
Y1 - 1986
N2 - The efficiency of some components of the host defense system has been evaluated in 32 atopic patients with rhinitis, asthma or asthma and rhinitis. No alterations in components of complement (C3 and C4), serum immunoglobulins (IgG, IgA, and IgM) and neutrophil functional parameters were found. As expected, serum IgE values were higher than in controls. A decreased percentage of total circulating T lymphocytes, an increased percentage of Ia1-positive cells, but normal values of OKT4- and OKT8-positive T lymphocytes were demonstrated. However, a greater heterogeneity in the distribution of the suppressor-cytotoxic subset was shown in atopic patients.
AB - The efficiency of some components of the host defense system has been evaluated in 32 atopic patients with rhinitis, asthma or asthma and rhinitis. No alterations in components of complement (C3 and C4), serum immunoglobulins (IgG, IgA, and IgM) and neutrophil functional parameters were found. As expected, serum IgE values were higher than in controls. A decreased percentage of total circulating T lymphocytes, an increased percentage of Ia1-positive cells, but normal values of OKT4- and OKT8-positive T lymphocytes were demonstrated. However, a greater heterogeneity in the distribution of the suppressor-cytotoxic subset was shown in atopic patients.
KW - Host defense system
KW - Polymorphonuclear neutrophil function tests
KW - T-lymphocyte subsets
UR - http://www.scopus.com/inward/record.url?scp=0022834333&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022834333&partnerID=8YFLogxK
U2 - 10.1159/000195105
DO - 10.1159/000195105
M3 - Article
C2 - 2951829
AN - SCOPUS:0022834333
VL - 50
SP - 83
EP - 91
JO - Respiration; international review of thoracic diseases
JF - Respiration; international review of thoracic diseases
SN - 0025-7931
ER -