The aim of this work is to investigate the use of iodine based contrast media in mammography with two different double exposure techniques: K-Edge Subtraction Mammography and Temporal Subtraction Mammography. Both techniques have been investigated by using monochromatic beams produced at a synchrotron radiation facility and conventional beams obtained with a clinical digital mammography system. A dedicated three-component phantom containing cavities filled with different iodine concentrations has been developed and used for measurements. For each technique, information about the minimum iodine concentration which provides a significant enhancement of the detectability of the pathology by minimizing the risk due to high dose and high concentration of contrast medium has been obtained. In particular for cavities of 5 and 8 mm of diameter filled with iodine solutions (0, 2, 4, 8, 16, 32 mg / ml), the minimum concentrations needed to obtain a contrast-to-noise ratio of 5 with a mean glandular dose of 2 mGy have been obtained.
|Number of pages||4|
|Journal||Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment|
|Publication status||Published - Oct 1 2007|
- Contrast medium
ASJC Scopus subject areas
- Nuclear and High Energy Physics