Abstract
The new commercial assay GenoType Mycobacterium, intended for the identification of mycobacteria, was evaluated with a panel of 197 strains belonging to 86 different taxa. The system, which relies on solid-phase reverse hybridization, is composed of two different kits: GenoType CM for the identification of more frequently detected mycobacterial species and GenoType AS for less common species. The sensitivity and specificity were 97.9% and 92.4% for the CM kit and 99.3% and 99.4% for the AS kit. Our results show that the system may represent a useful tool to substantially enlarge the number of mycobacteria that can be reliably identified in clinical laboratories.
| Original language | English |
|---|---|
| Pages (from-to) | 334-339 |
| Number of pages | 6 |
| Journal | Journal of Clinical Microbiology |
| Volume | 44 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2006 |
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ASJC Scopus subject areas
- Microbiology (medical)
- Microbiology
Cite this
Evaluation of the new GenoType Mycobacterium assay for identification of mycobacterial species. / Russo, Cristina; Tortoli, Enrico; Menichella, Donato.
In: Journal of Clinical Microbiology, Vol. 44, No. 2, 02.2006, p. 334-339.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evaluation of the new GenoType Mycobacterium assay for identification of mycobacterial species
AU - Russo, Cristina
AU - Tortoli, Enrico
AU - Menichella, Donato
PY - 2006/2
Y1 - 2006/2
N2 - The new commercial assay GenoType Mycobacterium, intended for the identification of mycobacteria, was evaluated with a panel of 197 strains belonging to 86 different taxa. The system, which relies on solid-phase reverse hybridization, is composed of two different kits: GenoType CM for the identification of more frequently detected mycobacterial species and GenoType AS for less common species. The sensitivity and specificity were 97.9% and 92.4% for the CM kit and 99.3% and 99.4% for the AS kit. Our results show that the system may represent a useful tool to substantially enlarge the number of mycobacteria that can be reliably identified in clinical laboratories.
AB - The new commercial assay GenoType Mycobacterium, intended for the identification of mycobacteria, was evaluated with a panel of 197 strains belonging to 86 different taxa. The system, which relies on solid-phase reverse hybridization, is composed of two different kits: GenoType CM for the identification of more frequently detected mycobacterial species and GenoType AS for less common species. The sensitivity and specificity were 97.9% and 92.4% for the CM kit and 99.3% and 99.4% for the AS kit. Our results show that the system may represent a useful tool to substantially enlarge the number of mycobacteria that can be reliably identified in clinical laboratories.
UR - http://www.scopus.com/inward/record.url?scp=32344448560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=32344448560&partnerID=8YFLogxK
U2 - 10.1128/JCM.44.2.334-339.2006
DO - 10.1128/JCM.44.2.334-339.2006
M3 - Article
C2 - 16455880
AN - SCOPUS:32344448560
VL - 44
SP - 334
EP - 339
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 2
ER -