Evaluation of the peritoneal equilibration test in children on chronic peritoneal dialysis

A. Edefonti, M. Picca, R. Galato, S. Guez, M. Giani, L. Ghio, B. Damiani, A. Dal Col, C. Santeramo

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Abstract

The peritoneal equilibration test (PET) is routinely performed in adults treated with chronic peritoneal dialysis to assess the peritoneal transport rate and to optimize treatment prescription. Only a few and not well-standardized studies on the PET have been reported in children. Twenty-six PETs were performed in 16 children, mean age 10.9±4.9 years, mean body weight (BW) 26.8±11.9 kg, treated with nightly intermittent peritoneal dialysis (NIPD). The PET was performed according to Twardowski. Forty mL/kg BW of 2.27% glucose solution were infused at a rate of 10 mL/kg BW every 2 minutes. In the simplified test, dialysate samples were taken at dwell times 0, 2 and 4 hours for glucose and creatinine. A blood sample was taken after a 2-hour dwell time tor the same parameters. The standard PET (8 patients) consisted of dialysate samples at 0, 15, 30, 60, 120, and 240 minutes and blood samples at 0 and 240 minutes. Mean DIP ratio for corrected creatinine and D/D0 ratio for glucose at 2 hours were 51.6±11.6 and 50.4±9, respectively; at 4 hours 69.6±12 and 34.4±9.8, respectively. There was good correlation between D/P creatinine and D/D0 glucose at 4 hours (p0 glucose lower than those of adults as reported by Twardowski. A consistent percentage of children had, nevertheless, a low-average or low transport rate. Standard PET is required in case of automated peritoneal dialysis prescription.

Original languageEnglish
JournalPeritoneal Dialysis International
Volume13
Issue numberSUPPL. 2
Publication statusPublished - 1993

Keywords

  • Children
  • Chronic peritoneal dialysis
  • Peritoneal equilibration test

ASJC Scopus subject areas

  • Nephrology

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