Abstract
A selective rubella immunization program was carried out in the Siena (Italy) area since 1984. 912 schoolgirls aged 10 to 18 were screened for rubella antibodies. Seropositivity rates, increasing with age, appeared quite heterogenous among subjects living in different villages. Seronegative girls were partly voluntarily immunized with RA 27/3 live attenuated rubella vaccine. Serological and clinical controls performed on 238 subjects one month after immunization showed a 99.6% vaccine-induced seroconversion rate and mild post-vaccinal reactions in 26% of vaccinees. Serological control performed, on 172 subjects, at 8-12 days after vaccination revealed that in most cases vaccine induced haemagglutination-inhibiting antibodies are not detectable at the time. The results are discussed in relation to a forthcoming introduction of compulsory rubella vaccination in our Country.
| Original language | Italian |
|---|---|
| Pages (from-to) | 97-105 |
| Number of pages | 9 |
| Journal | Quaderni Sclavo di diagnostica clinica e di laboratorio |
| Volume | 24 |
| Issue number | 1-4 |
| Publication status | Published - Jan 1988 |
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ASJC Scopus subject areas
- Medicine(all)
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Valutazione della risposta immunitaria specifica dopo vaccinazione anti-rosolia. / Cellesi, C.; Rossolini, A.; Rossolini, G. M.; Bianchi Bandinelli, M. L.; Grazia Cusi, M.; Egisto Valensin, P.
In: Quaderni Sclavo di diagnostica clinica e di laboratorio, Vol. 24, No. 1-4, 01.1988, p. 97-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Valutazione della risposta immunitaria specifica dopo vaccinazione anti-rosolia.
AU - Cellesi, C.
AU - Rossolini, A.
AU - Rossolini, G. M.
AU - Bianchi Bandinelli, M. L.
AU - Grazia Cusi, M.
AU - Egisto Valensin, P.
PY - 1988/1
Y1 - 1988/1
N2 - A selective rubella immunization program was carried out in the Siena (Italy) area since 1984. 912 schoolgirls aged 10 to 18 were screened for rubella antibodies. Seropositivity rates, increasing with age, appeared quite heterogenous among subjects living in different villages. Seronegative girls were partly voluntarily immunized with RA 27/3 live attenuated rubella vaccine. Serological and clinical controls performed on 238 subjects one month after immunization showed a 99.6% vaccine-induced seroconversion rate and mild post-vaccinal reactions in 26% of vaccinees. Serological control performed, on 172 subjects, at 8-12 days after vaccination revealed that in most cases vaccine induced haemagglutination-inhibiting antibodies are not detectable at the time. The results are discussed in relation to a forthcoming introduction of compulsory rubella vaccination in our Country.
AB - A selective rubella immunization program was carried out in the Siena (Italy) area since 1984. 912 schoolgirls aged 10 to 18 were screened for rubella antibodies. Seropositivity rates, increasing with age, appeared quite heterogenous among subjects living in different villages. Seronegative girls were partly voluntarily immunized with RA 27/3 live attenuated rubella vaccine. Serological and clinical controls performed on 238 subjects one month after immunization showed a 99.6% vaccine-induced seroconversion rate and mild post-vaccinal reactions in 26% of vaccinees. Serological control performed, on 172 subjects, at 8-12 days after vaccination revealed that in most cases vaccine induced haemagglutination-inhibiting antibodies are not detectable at the time. The results are discussed in relation to a forthcoming introduction of compulsory rubella vaccination in our Country.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023671501&partnerID=8YFLogxK
M3 - Articolo
C2 - 3268925
AN - SCOPUS:0023671501
VL - 24
SP - 97
EP - 105
JO - Quaderni Sclavo di diagnostica clinica e di laboratorio
JF - Quaderni Sclavo di diagnostica clinica e di laboratorio
SN - 0033-4979
IS - 1-4
ER -