Evaluation of tuberculosis treatment results in Italy, report 1999

Research output: Contribution to journalArticle

Abstract

In Italy no national data on tuberculosis (TB) treatment results was available. In 1995 the A.I.P.O. (Italian Association of Hospital Pneumologists) TB Study Group, in collaboration with the Istituto Superiore di Sanità (technical branch of the Ministry of Health) started a prospective monitoring activity based on the World Health Organisation and the International Union Against Tuberculosis and Lung Disease recommendations. Data was collected from a representative network of TB units nationwide, managing a significant proportion of all TB cases notified in Italy each year. Aim of this study was to analyse the casefinding and treatment results for 1999. 906 TB cases were reported (61.2% males; 36.2% immigrants), 714 (78.8%) being new cases. Of these cases 639 (70.5%) were pulmonary, 221 (24.4%) extrapulmonary cases and 46 (5.1%) both pulmonary and extrapulmonary. The main risk-factors for TB were history of recent contact, diabetes and alcohol abuse among native Italians, the human immunodeficiency virus-sieropositive status and history of recent contact among immigrants. The majority of immigrants came from Africa and Asia, and had stayed in Italy for more than 24 months before diagnosis of TB. Thirty-five per cent (320/906) of pulmonary patients had a positive direct sputum smear examination for alcohol acid-fast bacilli; 22.5% were resistant to any drug (from combined monoresistance to rifampicin: 1.6%; combined multi-drug resistance: 4.8%). In 97% of cases the duration of treatment was

Original languageEnglish
Pages (from-to)297-305
Number of pages9
JournalMonaldi Archives for Chest Disease - Cardiac Series
Volume57
Issue number5-6
Publication statusPublished - Oct 2002

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Italy
Tuberculosis
Lung
Therapeutics
Chronic Disease Hospitals
Multiple Drug Resistance
Rifampin
Sputum
Population Groups
Bacillus
Alcoholism
Alcohols
HIV
Acids
Health
Pharmaceutical Preparations

Keywords

  • Cohort analysis
  • Italy
  • Treatment outcomes
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Evaluation of tuberculosis treatment results in Italy, report 1999",
abstract = "In Italy no national data on tuberculosis (TB) treatment results was available. In 1995 the A.I.P.O. (Italian Association of Hospital Pneumologists) TB Study Group, in collaboration with the Istituto Superiore di Sanit{\`a} (technical branch of the Ministry of Health) started a prospective monitoring activity based on the World Health Organisation and the International Union Against Tuberculosis and Lung Disease recommendations. Data was collected from a representative network of TB units nationwide, managing a significant proportion of all TB cases notified in Italy each year. Aim of this study was to analyse the casefinding and treatment results for 1999. 906 TB cases were reported (61.2{\%} males; 36.2{\%} immigrants), 714 (78.8{\%}) being new cases. Of these cases 639 (70.5{\%}) were pulmonary, 221 (24.4{\%}) extrapulmonary cases and 46 (5.1{\%}) both pulmonary and extrapulmonary. The main risk-factors for TB were history of recent contact, diabetes and alcohol abuse among native Italians, the human immunodeficiency virus-sieropositive status and history of recent contact among immigrants. The majority of immigrants came from Africa and Asia, and had stayed in Italy for more than 24 months before diagnosis of TB. Thirty-five per cent (320/906) of pulmonary patients had a positive direct sputum smear examination for alcohol acid-fast bacilli; 22.5{\%} were resistant to any drug (from combined monoresistance to rifampicin: 1.6{\%}; combined multi-drug resistance: 4.8{\%}). In 97{\%} of cases the duration of treatment was",
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