Evidence for central organization of cardiovascular rhythms

Nicola Montano, Alberto Porta, Alberto Malliani

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Spectral analysis of heart rate and arterial pressure variabilities is a powerful noninvasive tool that is increasingly used to infer alterations of cardiovascular autonomic regulation in a variety of physiological and pathophysiological conditions such as hypertension, myocardial infarction, and congestive heart failure. A most important methodological issue to properly interpret the results obtained by the spectral analysis of cardiovascular variability signals is represented by the attribution of neurophysiologicai correlates to these spectral components. In this regard, recent application of spectral techniques to the evaluation of the oscillatory properties of sympathetic efferent activity in animals as well as in humans offers a new approach to a better understanding of the relationship between cardiovascular oscillations and autonomic regulation. The data so far collected seem to suggest the presence of a centrally organized neural code, characterized by excitatory and inhibitory neural mechanisms subserving the genesis and the regulation of cardiovascular oscillations concerning the major variables of autonomic regulation.

Original languageEnglish
Pages (from-to)299-306
Number of pages8
JournalAnnals of the New York Academy of Sciences
Volume940
Publication statusPublished - 2001

Fingerprint

Spectrum analysis
Arterial Pressure
Heart Failure
Heart Rate
Myocardial Infarction
Hypertension
Animals
Rhythm
Spectrality
Oscillation
Spectral Analysis

Keywords

  • Baroreflex mechanisms
  • Heart rate variability
  • Spectral analysis
  • Sympathetic activity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Evidence for central organization of cardiovascular rhythms. / Montano, Nicola; Porta, Alberto; Malliani, Alberto.

In: Annals of the New York Academy of Sciences, Vol. 940, 2001, p. 299-306.

Research output: Contribution to journalArticle

@article{e71bccb2ff7a4db7acbd8cb45b075772,
title = "Evidence for central organization of cardiovascular rhythms",
abstract = "Spectral analysis of heart rate and arterial pressure variabilities is a powerful noninvasive tool that is increasingly used to infer alterations of cardiovascular autonomic regulation in a variety of physiological and pathophysiological conditions such as hypertension, myocardial infarction, and congestive heart failure. A most important methodological issue to properly interpret the results obtained by the spectral analysis of cardiovascular variability signals is represented by the attribution of neurophysiologicai correlates to these spectral components. In this regard, recent application of spectral techniques to the evaluation of the oscillatory properties of sympathetic efferent activity in animals as well as in humans offers a new approach to a better understanding of the relationship between cardiovascular oscillations and autonomic regulation. The data so far collected seem to suggest the presence of a centrally organized neural code, characterized by excitatory and inhibitory neural mechanisms subserving the genesis and the regulation of cardiovascular oscillations concerning the major variables of autonomic regulation.",
keywords = "Baroreflex mechanisms, Heart rate variability, Spectral analysis, Sympathetic activity",
author = "Nicola Montano and Alberto Porta and Alberto Malliani",
year = "2001",
language = "English",
volume = "940",
pages = "299--306",
journal = "Annals of the New York Academy of Sciences",
issn = "0077-8923",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Evidence for central organization of cardiovascular rhythms

AU - Montano, Nicola

AU - Porta, Alberto

AU - Malliani, Alberto

PY - 2001

Y1 - 2001

N2 - Spectral analysis of heart rate and arterial pressure variabilities is a powerful noninvasive tool that is increasingly used to infer alterations of cardiovascular autonomic regulation in a variety of physiological and pathophysiological conditions such as hypertension, myocardial infarction, and congestive heart failure. A most important methodological issue to properly interpret the results obtained by the spectral analysis of cardiovascular variability signals is represented by the attribution of neurophysiologicai correlates to these spectral components. In this regard, recent application of spectral techniques to the evaluation of the oscillatory properties of sympathetic efferent activity in animals as well as in humans offers a new approach to a better understanding of the relationship between cardiovascular oscillations and autonomic regulation. The data so far collected seem to suggest the presence of a centrally organized neural code, characterized by excitatory and inhibitory neural mechanisms subserving the genesis and the regulation of cardiovascular oscillations concerning the major variables of autonomic regulation.

AB - Spectral analysis of heart rate and arterial pressure variabilities is a powerful noninvasive tool that is increasingly used to infer alterations of cardiovascular autonomic regulation in a variety of physiological and pathophysiological conditions such as hypertension, myocardial infarction, and congestive heart failure. A most important methodological issue to properly interpret the results obtained by the spectral analysis of cardiovascular variability signals is represented by the attribution of neurophysiologicai correlates to these spectral components. In this regard, recent application of spectral techniques to the evaluation of the oscillatory properties of sympathetic efferent activity in animals as well as in humans offers a new approach to a better understanding of the relationship between cardiovascular oscillations and autonomic regulation. The data so far collected seem to suggest the presence of a centrally organized neural code, characterized by excitatory and inhibitory neural mechanisms subserving the genesis and the regulation of cardiovascular oscillations concerning the major variables of autonomic regulation.

KW - Baroreflex mechanisms

KW - Heart rate variability

KW - Spectral analysis

KW - Sympathetic activity

UR - http://www.scopus.com/inward/record.url?scp=0034937351&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034937351&partnerID=8YFLogxK

M3 - Article

C2 - 11458687

AN - SCOPUS:0034937351

VL - 940

SP - 299

EP - 306

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

SN - 0077-8923

ER -