Evidence for progressive gray matter loss in patients with relapsing-remitting MS

P. Valsasina, B. Benedetti, M. Rovaris, M. P. Sormani, G. Comi, Massimo Filippi

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Little is known about the temporal evolution of gray matter damage occurring early in the course of multiple sclerosis (MS). The authors investigated the evolution of gray matter volume loss in 117 patients with relapsing-remitting MS, scanned monthly for a 9-month period. Time-trend analysis revealed a decrease of gray matter volumes over the study period (p <0.001). This study shows that gray matter damage in relapsing-remitting MS evolves markedly over a short period of observation.

Original languageEnglish
Pages (from-to)1126-1128
Number of pages3
JournalNeurology
Volume65
Issue number7
DOIs
Publication statusPublished - Oct 11 2005

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Relapsing-Remitting Multiple Sclerosis
Multiple Sclerosis
Observation
Gray Matter

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Evidence for progressive gray matter loss in patients with relapsing-remitting MS. / Valsasina, P.; Benedetti, B.; Rovaris, M.; Sormani, M. P.; Comi, G.; Filippi, Massimo.

In: Neurology, Vol. 65, No. 7, 11.10.2005, p. 1126-1128.

Research output: Contribution to journalArticle

Valsasina, P. ; Benedetti, B. ; Rovaris, M. ; Sormani, M. P. ; Comi, G. ; Filippi, Massimo. / Evidence for progressive gray matter loss in patients with relapsing-remitting MS. In: Neurology. 2005 ; Vol. 65, No. 7. pp. 1126-1128.
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