Abstract
Infants of diabetic mothers (IDMs) have lower bone mineral content than control subjects at birth. We measured cord blood propeptide of type I procollagen (PICP), a marker of bone formation, and telopeptide of type I collagen (ICTP), a marker of bone resorption, in 25 term IDMs and 20 term control subjects. Concentrations of ICTP were higher in IDMs than in control subjects; there was no difference in PICP concentrations. We conclude that osteoclastic activity appears to be higher in IDMs than in control subjects in utero. (J P EDIATR 1995;126:796 8).
| Original language | English |
|---|---|
| Pages (from-to) | 796-798 |
| Number of pages | 3 |
| Journal | Journal of Pediatrics |
| Volume | 126 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1995 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Evidence of increased intrauterine bone resorption in term infants of mothers with insulin-dependent diabetes. / Demarini, Sergio; Specker, Bonny L.; Sierra, Rosa I.; Miodovnik, Menachem; Tsang, Reginald C.
In: Journal of Pediatrics, Vol. 126, No. 5, 1995, p. 796-798.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evidence of increased intrauterine bone resorption in term infants of mothers with insulin-dependent diabetes
AU - Demarini, Sergio
AU - Specker, Bonny L.
AU - Sierra, Rosa I.
AU - Miodovnik, Menachem
AU - Tsang, Reginald C.
PY - 1995
Y1 - 1995
N2 - Infants of diabetic mothers (IDMs) have lower bone mineral content than control subjects at birth. We measured cord blood propeptide of type I procollagen (PICP), a marker of bone formation, and telopeptide of type I collagen (ICTP), a marker of bone resorption, in 25 term IDMs and 20 term control subjects. Concentrations of ICTP were higher in IDMs than in control subjects; there was no difference in PICP concentrations. We conclude that osteoclastic activity appears to be higher in IDMs than in control subjects in utero. (J P EDIATR 1995;126:796 8).
AB - Infants of diabetic mothers (IDMs) have lower bone mineral content than control subjects at birth. We measured cord blood propeptide of type I procollagen (PICP), a marker of bone formation, and telopeptide of type I collagen (ICTP), a marker of bone resorption, in 25 term IDMs and 20 term control subjects. Concentrations of ICTP were higher in IDMs than in control subjects; there was no difference in PICP concentrations. We conclude that osteoclastic activity appears to be higher in IDMs than in control subjects in utero. (J P EDIATR 1995;126:796 8).
UR - http://www.scopus.com/inward/record.url?scp=0029019032&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029019032&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(95)70414-0
DO - 10.1016/S0022-3476(95)70414-0
M3 - Article
C2 - 7752009
AN - SCOPUS:0029019032
VL - 126
SP - 796
EP - 798
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 5
ER -