Abstract
The usefulness of evoked potentials (EPs) in the diagnosis of multiple sclerosis is limited by its relatively low sensitivity to subclinical lesions. However, they are still a good tool to assess the integrity of afferent and efferent path-ways and to quantify the severity of white matter involvement. Transversal and longitudinal studies have demonstrated good correlation between EP abnormalities and disability, suggesting that multimodal evoked potentials could be useful in monitoring the disease evolution in single patients and as surrogate end points in clinical trials.
| Original language | English |
|---|---|
| Journal | Neurological Sciences |
| Volume | 21 |
| Issue number | 8 |
| Publication status | Published - 2000 |
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Keywords
- Evoked potentials
- Monitoring
- Multiple sclerosis
ASJC Scopus subject areas
- Dermatology
- Clinical Neurology
- Psychiatry and Mental health
- Neuroscience(all)
Cite this
Evoked potentials in monitoring multiple sclerosis. / Leocani, L.; Medaglini, S.; Comi, G.
In: Neurological Sciences, Vol. 21, No. 8, 2000.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Evoked potentials in monitoring multiple sclerosis
AU - Leocani, L.
AU - Medaglini, S.
AU - Comi, G.
PY - 2000
Y1 - 2000
N2 - The usefulness of evoked potentials (EPs) in the diagnosis of multiple sclerosis is limited by its relatively low sensitivity to subclinical lesions. However, they are still a good tool to assess the integrity of afferent and efferent path-ways and to quantify the severity of white matter involvement. Transversal and longitudinal studies have demonstrated good correlation between EP abnormalities and disability, suggesting that multimodal evoked potentials could be useful in monitoring the disease evolution in single patients and as surrogate end points in clinical trials.
AB - The usefulness of evoked potentials (EPs) in the diagnosis of multiple sclerosis is limited by its relatively low sensitivity to subclinical lesions. However, they are still a good tool to assess the integrity of afferent and efferent path-ways and to quantify the severity of white matter involvement. Transversal and longitudinal studies have demonstrated good correlation between EP abnormalities and disability, suggesting that multimodal evoked potentials could be useful in monitoring the disease evolution in single patients and as surrogate end points in clinical trials.
KW - Evoked potentials
KW - Monitoring
KW - Multiple sclerosis
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UR - http://www.scopus.com/inward/citedby.url?scp=0042349234&partnerID=8YFLogxK
M3 - Article
C2 - 11205369
AN - SCOPUS:0042349234
VL - 21
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 8
ER -