Evolution of migraine-associated symptoms in menstrually related migraine following symptomatic treatment with almotriptan

Gianni Allais, Giancarlo Acuto, Chiara Benedetto, Giovanni D'Andrea, Licia Grazzi, Gian Camillo Manzoni, Franca Moschiano, Florindo D'Onofrio, Fabio Valguarnera, Gennaro Bussone

Research output: Contribution to journalArticle

Abstract

In addition to headache, migraine is characterized by a series of symptoms that negatively affects the quality of life of patients. Generally, these are represented by nausea, vomiting, photophobia, phonophobia and osmophobia, with a cumulative percentage of the onset in about 90% of the patients. From this point of view, menstrually related migraine-a particularly difficult-to-treat form of primary headache-is no different from other forms of migraine. Symptomatic treatment should therefore be evaluated not only in terms of headache relief, but also by considering its effect on these migraine-associated symptoms (MAS). Starting from the data collected in a recently completed multicentre, randomized, double-blind, placebo-controlled, cross-over study with almotriptan in menstrually related migraine, an analysis of the effect of this drug on the evolution of MAS was performed. Data suggest that almotriptan shows excellent efficacy on MAS in comparison to the placebo, with a significant reduction in the percentages of suffering patients over a 2-h period of time.

Original languageEnglish
JournalNeurological Sciences
Volume31
Issue numberSUPPL.1
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Acute treatment
  • Almotriptan
  • Menstrual migraine
  • Migraine-associated symptoms

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)

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    Allais, G., Acuto, G., Benedetto, C., D'Andrea, G., Grazzi, L., Manzoni, G. C., Moschiano, F., D'Onofrio, F., Valguarnera, F., & Bussone, G. (2010). Evolution of migraine-associated symptoms in menstrually related migraine following symptomatic treatment with almotriptan. Neurological Sciences, 31(SUPPL.1). https://doi.org/10.1007/s10072-010-0302-9