Surgical resection is the gold standard in the treatment of colorectal liver metastases. Extension of the indications has, not surprisingly, determined an increase in the recurrence rates, underlining the need for appropriate selection of those patients who may benefit most from surgery. However, literature data suggest that the presence of any combination of pre-operative factors should not be used as an absolute contraindication to resection. Instead, colorectal liver metastases should be treated by resection whenever liver resection is technically feasible, with curative intent.
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