TY - JOUR
T1 - Evolution of the endoplasmic reticulum and the Golgi complex
AU - Mironov, Alexander A.
AU - Banin, Victor V.
AU - Sesorova, Irina S.
AU - Dolgikh, Viacheslav V.
AU - Luini, Alberto
AU - Beznoussenko, Galina V.
PY - 2007
Y1 - 2007
N2 - By analyzing the morpho-physiological features of the Golgi complex, its relationship with the endoplasmic reticulum in different species, and the molecular machineries involved in intracellular transport, we conclude that; (1) all eukaryotic cells have either Golgi complexes or remnants thereof; (2) all eukaryotic cells have a large minimal set of proteins that are involved in intracellular transport; and (3) several indispensable molecular machines are always present in secreting eukaryotic cells. Using this information, our data about mechanisms of intra-Golgi transport and phylogenetic analysis of several molecular machines, we propose a model for the evolution of the Golgi complex and the endoplasmic reticulum.
AB - By analyzing the morpho-physiological features of the Golgi complex, its relationship with the endoplasmic reticulum in different species, and the molecular machineries involved in intracellular transport, we conclude that; (1) all eukaryotic cells have either Golgi complexes or remnants thereof; (2) all eukaryotic cells have a large minimal set of proteins that are involved in intracellular transport; and (3) several indispensable molecular machines are always present in secreting eukaryotic cells. Using this information, our data about mechanisms of intra-Golgi transport and phylogenetic analysis of several molecular machines, we propose a model for the evolution of the Golgi complex and the endoplasmic reticulum.
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U2 - 10.1007/978-0-387-74021-8_5
DO - 10.1007/978-0-387-74021-8_5
M3 - Article
AN - SCOPUS:84934437323
VL - 607
SP - 61
EP - 72
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
SN - 0065-2598
ER -