Evolutive study of relapsing-remitting multiple sclerosis with cervical proton magnetic resonance spectroscopy: A case report

Luca Albini Riccioli, A. F. Marliani, V. Clementi, I. Bartolomei, R. Agati, M. Leonardi

Research output: Contribution to journalArticlepeer-review

Abstract

We used quantitative proton magnetic resonance spectroscopy (1H-MRS) to evaluate mean relative concentrations ratios for NAA, Cr, Cho and ml during the study of cervical spinal cord plaques in a relapsing-remitting multiple sclerosis (RRMS). A cervical spine MR exam was repeated five times on the following days for two months starting from the onset of a relapse phase, using a 3T whole-body system, with the voxel placed along the demyelinazation lesion. The quantification results were compared with the healthy metabolites content. Quantitative cervical spectroscopy is a reliable tool and can offer important metabolic information as already used on the brain to evaluate the severity, progression and pathogenesis of multiple sclerosis.

Original languageEnglish
Pages (from-to)511-517
Number of pages7
JournalNeuroradiology Journal
Volume21
Issue number4
Publication statusPublished - Aug 2008

Keywords

  • 3 Tesla
  • Metabolite quantification
  • Proton magnetic resonance spectroscopy
  • Relapsing-remitting multiple sclerosis
  • Spinal cord

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging

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