Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours

Sandro Dallorso; G. Dini; R. Ladenstein; A. Cama; C. Milanaccio; S. Barra; B. Cappelli; M. L. Garrè

doi:10.1038/sj.bmt.1704841

Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours

Sandro Dallorso, G. Dini, R. Ladenstein, A. Cama, C. Milanaccio, S. Barra, B. Cappelli, M. L. Garrè

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Abstract

Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the role of high-dose chemotherapy and haematopoietic stem cell rescue. Patients with high-grade glial tumours, primitive neuroectodermal tumours and high-risk medulloblastoma usually fare poorly. The indicators of bad prognosis are metastatic status, extent of resection and age. Children

Original language	English
Journal	Bone Marrow Transplantation
Volume	35
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1038/sj.bmt.1704841
Publication status	Published - Mar 2005

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Keywords

Autologous stem cell transplantation
Brain tumours
Childhood

ASJC Scopus subject areas

Hematology
Transplantation

Cite this

Dallorso, S., Dini, G., Ladenstein, R., Cama, A., Milanaccio, C., Barra, S., Cappelli, B., & Garrè, M. L. (2005). Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours. Bone Marrow Transplantation, 35(SUPPL. 1). https://doi.org/10.1038/sj.bmt.1704841

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10.1038/sj.bmt.1704841