Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours

Sandro Dallorso, G. Dini, R. Ladenstein, A. Cama, C. Milanaccio, S. Barra, B. Cappelli, M. L. Garrè

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the role of high-dose chemotherapy and haematopoietic stem cell rescue. Patients with high-grade glial tumours, primitive neuroectodermal tumours and high-risk medulloblastoma usually fare poorly. The indicators of bad prognosis are metastatic status, extent of resection and age. Children

Original languageEnglish
JournalBone Marrow Transplantation
Volume35
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Mar 2005

Fingerprint

Brain Neoplasms
Primitive Neuroectodermal Tumors
Drug Therapy
Medulloblastoma
Second Primary Neoplasms
Hematopoietic Stem Cells
Neuroglia
Neoplasms
Radiotherapy
Therapeutics

Keywords

  • Autologous stem cell transplantation
  • Brain tumours
  • Childhood

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours. / Dallorso, Sandro; Dini, G.; Ladenstein, R.; Cama, A.; Milanaccio, C.; Barra, S.; Cappelli, B.; Garrè, M. L.

In: Bone Marrow Transplantation, Vol. 35, No. SUPPL. 1, 03.2005.

Research output: Contribution to journalArticle

@article{b29de5eb3a304799994417b21cce9ee2,
title = "Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours",
abstract = "Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the role of high-dose chemotherapy and haematopoietic stem cell rescue. Patients with high-grade glial tumours, primitive neuroectodermal tumours and high-risk medulloblastoma usually fare poorly. The indicators of bad prognosis are metastatic status, extent of resection and age. Children",
keywords = "Autologous stem cell transplantation, Brain tumours, Childhood",
author = "Sandro Dallorso and G. Dini and R. Ladenstein and A. Cama and C. Milanaccio and S. Barra and B. Cappelli and Garr{\`e}, {M. L.}",
year = "2005",
month = "3",
doi = "10.1038/sj.bmt.1704841",
language = "English",
volume = "35",
journal = "Bone Marrow Transplantation",
issn = "0268-3369",
publisher = "Nature Publishing Group",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Evolving role of myeloablative chemotherapy in the treatment of childhood brain tumours

AU - Dallorso, Sandro

AU - Dini, G.

AU - Ladenstein, R.

AU - Cama, A.

AU - Milanaccio, C.

AU - Barra, S.

AU - Cappelli, B.

AU - Garrè, M. L.

PY - 2005/3

Y1 - 2005/3

N2 - Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the role of high-dose chemotherapy and haematopoietic stem cell rescue. Patients with high-grade glial tumours, primitive neuroectodermal tumours and high-risk medulloblastoma usually fare poorly. The indicators of bad prognosis are metastatic status, extent of resection and age. Children

AB - Primary brain tumours, a heterogeneous group of cancer that constitute the second most common cancer in childhood, were historically treated with neurosurgical resection and radiation therapy. Chemotherapy has proven to be beneficial for some histological types, which has since led to exploration of the role of high-dose chemotherapy and haematopoietic stem cell rescue. Patients with high-grade glial tumours, primitive neuroectodermal tumours and high-risk medulloblastoma usually fare poorly. The indicators of bad prognosis are metastatic status, extent of resection and age. Children

KW - Autologous stem cell transplantation

KW - Brain tumours

KW - Childhood

UR - http://www.scopus.com/inward/record.url?scp=18144430659&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18144430659&partnerID=8YFLogxK

U2 - 10.1038/sj.bmt.1704841

DO - 10.1038/sj.bmt.1704841

M3 - Article

C2 - 15812527

AN - SCOPUS:18144430659

VL - 35

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

SN - 0268-3369

IS - SUPPL. 1

ER -